Coxsackie Adenovirus Receptor anticorps (C-Term)

N° du produit ABIN3029697

Détail du produit anti-Coxsackie Adenovirus Receptor anticorps

Antigène: Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Coxsackie Adenovirus Receptor est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of human Coxsackie Adenovirus Receptor (YSKTQYNQVPSEDFER) was used as the immunogen for this CAR antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the CAR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the CAR antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Coxsackie Adenovirus Receptor

Antigène: Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))

Autre désignation: CAR Coxsackie Adenovirus Receptor (CXADR Produits)

Synonymes: anticorps CAR, anticorps CAR4/6, anticorps HCAR, anticorps Car1, anticorps car, anticorps cb331, anticorps fb76g12, anticorps wu:fb76g12, anticorps 2610206D03Rik, anticorps AU016810, anticorps AW553441, anticorps MCAR, anticorps MCVADR, anticorps hcar, anticorps xCAR, anticorps CXADR, anticorps CXADR, Ig-like cell adhesion molecule, anticorps coxsackie virus and adenovirus receptor, anticorps CXADR, Ig-like cell adhesion molecule L homeolog, anticorps CXADR, anticorps Cxadr, anticorps cxadr, anticorps cxadr.L

Sujet: Coxsackie virus and adenovirus receptor is a protein that in humans is encoded by the CXADR gene, also known as CAR, CVB3-binding protein, and Coxsackievirus B-adenovirus receptor. The cDNA encodes a predicted 365-amino acid polypeptide that contains a single transmembrane domain and is a member of the immunoglobulin superfamily. By Northern blot analysis, the highest expression of 1.4-kb and 6-kb transcripts are in pancreas, brain, heart, small intestine, testis, and prostate, lower expression in liver and lung, and no expression in kidney, placenta, peripheral blood leukocytes, thymus, and spleen. In comparison, mouse CAR showed highest expression in liver, and lower levels in kidney, heart, lung, and brain. The protein encoded by this gene is a type I membrane receptor for group B coxsackie viruses and subgroup C adenoviruses. Pseudogenes of this gene are found on chromosomes 15, 18, and 21. CAR is strongly expressed in the developing central nervous system. It functions as a homophilic and also as a heterophilic cell adhesion molecule through its interactions with extracellular matrix glycoproteins , such as: fibronectin, agrin, laminin-1 and tenascin-R.

UniProt: P78310

Pathways: Cell-Cell Junction Organization