DICER1 anticorps (AA 1-195)

N° du produit ABIN3030723

Détail du produit anti-DICER1 anticorps

Antigène: DICER1 (Dicer 1, Ribonuclease Type III (DICER1))

Épitope: AA 1-195

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DICER1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 1-195) was used as the immunogen for this Dicer antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the Dicer antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Dicer antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur DICER1

Antigène: DICER1 (Dicer 1, Ribonuclease Type III (DICER1))

Autre désignation: Dicer (DICER1 Produits)

Synonymes: anticorps dcr1, anticorps dicer, anticorps herna, anticorps DICER1, anticorps dicer1, anticorps 1110006F08Rik, anticorps D12Ertd7e, anticorps mKIAA0928, anticorps DCR1, anticorps Dicer, anticorps HERNA, anticorps MNG1, anticorps DICER, anticorps fc39d11, anticorps fc74b05, anticorps wu:fc39d11, anticorps wu:fc74b05, anticorps dicer 1, ribonuclease III, anticorps endoribonuclease Dicer, anticorps dicer 1, ribonuclease III S homeolog, anticorps dicer 1, ribonuclease type III, anticorps dicer 1 ribonuclease III, anticorps DICER1, anticorps CpipJ_CPIJ010534, anticorps dicer1, anticorps dicer1.S, anticorps Dicer1

Sujet: Dicer is an enzyme that in humans is encoded by the DICER1 gene. It is mapped to 14q32.13. The gene, a member of the ribonuclease III (RNaseIII) family, is involved in the generation of microRNAs (miRNAs), which modulate gene expression at the posttranscriptional level. The enzyme possesses an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. It is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. In addition, it is required for formation of the RNA induced silencing complex (RISC). Dicer also cleaves double-stranded RNA to produce short interfering RNAs (siRNAs) which target the selective destruction of complementary RNAs.

ID gène: 23405

Pathways: Regulatory RNA Pathways, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization