FOSB anticorps (N-Term)

N° du produit ABIN3030918

Détail du produit anti-FOSB anticorps

Antigène: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOSB est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the N-terminus of human FosB (MFQAFPGDYDSGSRC) was used as the immunogen for this FosB antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the FosB antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the FosB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur FOSB

Antigène: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Autre désignation: FosB (FOSB Produits)

Synonymes: anticorps FOSB, anticorps zgc:92354, anticorps AP-1, anticorps G0S3, anticorps GOS3, anticorps GOSB, anticorps fra-2, anticorps FBJ murine osteosarcoma viral oncogene homolog B, anticorps FosB proto-oncogene, AP-1 transcription factor subunit, anticorps FBJ osteosarcoma oncogene B, anticorps FOSB, anticorps fosb, anticorps Fosb

Sujet: FBJ murine osteosarcoma viral oncogene homolog B is a protein that in humans is encoded by the FOSB gene. It is a member of Fos gene family which consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. The proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Delta FOSB is a truncated splice variant of FOSB. It has been implicated in the development of drug addiction and control of the reward system in the brain, and is linked to changes in a number of other gene products such as CREB and sirtuins. It also regulates the commitment of mesenchymal precursor cells to the adipocyte or osteoblast lineage.

UniProt: P53539