GNB2L1 anticorps (AA 2-317)

N° du produit ABIN3031132

Détail du produit anti-GNB2L1 anticorps

Antigène: GNB2L1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1))

Épitope: AA 2-317

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GNB2L1 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 2-317) was used as the immunogen for this RACK1 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the RACK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the RACK1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur GNB2L1

Antigène: GNB2L1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1))

Autre désignation: RACK1 (GNB2L1 Produits)

Synonymes: anticorps MGC53289, anticorps GNB2L1, anticorps AL033335, anticorps GB-like, anticorps Gnb2-rs1, anticorps Rack1, anticorps p205, anticorps RACK1, anticorps H12.3, anticorps HLC-7, anticorps PIG21, anticorps rack1, anticorps wu:fb80d08, anticorps wu:fk65d12, anticorps gnb2-rs1, anticorps h12.3, anticorps hlc-7, anticorps pig21, anticorps C12-3, anticorps c12.3, anticorps guanine nucleotide binding protein, beta 2, related sequence 1, anticorps receptor for activated C kinase 1, anticorps guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1, anticorps receptor for activated C kinase 1 L homeolog, anticorps Guanine nucleotide-binding protein subunit beta-2-like 1, anticorps gnb2l1, anticorps RACK1, anticorps Rack1, anticorps rack1.L, anticorps rack-1

Sujet: Guanine nucleotide-binding protein subunit beta-2-like 1, also known as RACK1, is a 35 kDa protein that in humans is encoded by the GNB2L1 gene. It is mapped to 5q35.3. It is a major component of translating ribosomes, which harbor significant amounts of PKC. This gene can provide a physical and functional link between < a href=../search_result.php?search_txt=pkc>PKC signaling and ribosome activation. GNB2L1/RACK1 is also a mediator of agonist-induced Ca(2+) release. Additionally, it is an essential component of an oxygen-independent mechanism for regulating < a href=../search_result.php?search_txt=hif1a>HIF1A stability. Overexpression of RACK1 and PKC-alpha suppressed < a href=../search_result.php?search_txt=clock>CLOCK-BMAL1 transcriptional activity, and it stimulated phosphorylation of BMAL1 by PKC-alpha in vitro.

ID gène: 10399

Pathways: cAMP Metabolic Process, Positive Regulation of Endopeptidase Activity