MFN2 anticorps (AA 601-757)

N° du produit ABIN3031819

Détail du produit anti-MFN2 anticorps

Antigène: MFN2 (Mitofusin 2 (MFN2))

Épitope: AA 601-757

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MFN2 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 601-757) was used as the immunogen for this MFN2 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the MFN2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the MFN2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur MFN2

Antigène: MFN2 (Mitofusin 2 (MFN2))

Autre désignation: MFN2 (MFN2 Produits)

Synonymes: anticorps CG3869, anticorps Dmel\\CG3869, anticorps MARF, anticorps Marf-1, anticorps Mfn, anticorps anon-WO0125274.3, anticorps dMFN, anticorps dMfn, anticorps dmfn, anticorps marf, anticorps mfn, anticorps mfn2, anticorps MFN2, anticorps hsg, anticorps cmt2a, anticorps cprp1, anticorps cmt2a2, anticorps CMT2A, anticorps CMT2A2, anticorps CPRP1, anticorps HSG, anticorps D630023P19Rik, anticorps Fzo, anticorps mg:cb01g09, anticorps si:dkeyp-104h9.2, anticorps wu:fb79a11, anticorps mitofusin 2, anticorps Mitochondrial assembly regulatory factor, anticorps mitofusin-2, anticorps mitofusin 2 L homeolog, anticorps MFN2, anticorps Marf, anticorps mfn2, anticorps LOC100186475, anticorps Mfn2, anticorps mfn2.L

Sujet: Mitofusin-2 is a protein that in humans is encoded by the MFN2 gene. It is mapped to chromosome 1 and encodes a 757-amino acid protein that contains an ATP/GTP-binding site motif. This gene is expressed in many tissues and cell lines such as brain and KG-1 with the highest expression in heart and skeletal muscle. It has been found that MFN2 triggers mitochondrial energization, at least in part, by regulating OXPHOS expression through signals that are independent of its role as a mitochondrial fusion protein. And it contributes to the maintenance and operation of the mitochondrial network. Axonal CMT type 2A and autosomal dominant HMSN VI are caused by MFN2 and mutations of, which emphasizes its important role of mitochondrial function for both optic atrophies and peripheral neuropathies.

ID gène: 9927

Pathways: Skeletal Muscle Fiber Development