TNFRSF11A anticorps (N-Term)

N° du produit ABIN3032432

Détail du produit anti-TNFRSF11A anticorps

Antigène: TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFRSF11A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: An amino acid sequence from the N-terminus of human RANK (QIAPPCTSEKHYEHLG) was used as the immunogen for this RANK antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the RANK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the RANK antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur TNFRSF11A

Antigène: TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))

Autre désignation: RANK (TNFRSF11A Produits)

Synonymes: anticorps RANK, anticorps RGD1563614, anticorps TNFRSF11A, anticorps Ly109, anticorps ODFR, anticorps OFE, anticorps Rank, anticorps TRANCE-R, anticorps mRANK, anticorps CD265, anticorps FEO, anticorps LOH18CR1, anticorps OPTB7, anticorps OSTS, anticorps PDB2, anticorps TRANCER, anticorps TNF receptor superfamily member 11A, anticorps TNF receptor superfamily member 11a, anticorps tumor necrosis factor receptor superfamily, member 11a, NFKB activator, anticorps Tnfrsf11a, anticorps TNFRSF11A

Sujet: Receptor Activator of Nuclear Factor K B, also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is also expressed on dendritic cells and facilitates immune signaling. RANKL (Receptor Activator for Nuclear Factor K B Ligand) is found on the surface of stromal cells, osteoblasts, and T cells. By analysis of somatic cell and radiation hybrid panels, Anderson et al.(1997) mapped the RANK gene to 18q22.1.

UniProt: Q9Y6Q6

Pathways: Signalisation NF-kappaB