SDHB anticorps (AA 42-59)

N° du produit ABIN3032764

Détail du produit anti-SDHB anticorps

Antigène: SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))

Épitope: AA 42-59

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SDHB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: Amino acids 42-59 (FAIYRWDPDKAGDKPHMQ-human) were used as the immunogen for this SDHB antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the SDHB antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the SDHB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur SDHB

Antigène: SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))

Autre désignation: SDHB (SDHB Produits)

Synonymes: anticorps succinate dehydrogenase 2-3, anticorps CG3283, anticorps Dmel\\CG3283, anticorps Ip, anticorps SDH, anticorps SDH-IP, anticorps SDH-Ip, anticorps SDHb, anticorps sdhB, anticorps CWS2, anticorps IP, anticorps PGL4, anticorps SDH1, anticorps SDH2, anticorps SDHIP, anticorps 0710008N11Rik, anticorps fj46d06, anticorps wu:fj46d06, anticorps succinate dehydrogenase complex iron sulfur subunit B, anticorps succinate dehydrogenase [ubiquinone] iron-sulfur subunit 3, anticorps Succinate dehydrogenase, subunit B (iron-sulfur), anticorps succinate dehydrogenase complex subunit B, iron sulfur (Ip), anticorps succinate dehydrogenase complex, subunit B, iron sulfur (Ip), anticorps succinate dehydrogenase complex subunit B, iron sulfur (Ip) S homeolog, anticorps SDHB, anticorps SDH2-3, anticorps SdhB, anticorps sdhb, anticorps Sdhb, anticorps sdhb.S

Sujet: Succinate Dehydrogenase Complex, Subunit B, iron sulfur protein is a protein that in humans is encoded by the SDHB gene. It is one of four protein subunits forming succinate dehydrogenase, the other three being SDHA, SDHC and SDHD. The SDHB subunit is connected to the SDHA subunit on the hydrophilic, catalytic end of the SDH complex. The entire SDHB transcript is encoded by 8 exons within approximately 40 kb by Au et al(1995). Pollard et al.(2005) stated that the nuclear-encoded Krebs cycle enzymes fumarate hydratase and succinate dehydrogenases like SDHB act as tumor suppressors, and germline mutations in these genes predispose individuals to leiomyomas and renal cancer and to paragangliomas, respectively. In affected members of families with paragangliomas-4, mutations were identified in the SDHB gene.

UniProt: P21912