YES1 anticorps (N-Term)

N° du produit ABIN3042333

Détail du produit anti-YES1 anticorps

Antigène: YES1 (V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1))

Épitope: AA 7-35, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YES1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Tyrosine-protein kinase Yes(YES1) detection. Tested with WB, IHC-P in Human.

Séquence: KENKSPAIKY RPENTPEPVS TSVSHYGAE

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Tyrosine-protein kinase Yes(YES1) detection. Tested with WB, IHC-P in Human.
Gene Name: YES proto-oncogene 1, Src family tyrosine kinase
Protein Name: Tyrosine-protein kinase Yes

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human Yes1 (7-35aa KENKSPAIKYRPENTPEPVSTSVSHYGAE), different from the related mouse sequence by six amino acids, and from the related rat sequence by seven amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Yes1 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur YES1

Antigène: YES1 (V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1))

Autre désignation: YES1 (YES1 Produits)

Synonymes: anticorps HsT441, anticorps P61-YES, anticorps Yes, anticorps c-yes, anticorps yes, anticorps p61-Yes, anticorps hst441, anticorps p61-yes, anticorps YES, anticorps c-Yes, anticorps p60c-yes, anticorps YES proto-oncogene 1, Src family tyrosine kinase, anticorps YES proto-oncogene 1, Src family tyrosine kinase L homeolog, anticorps YES1, anticorps yes1.L, anticorps yes1, anticorps Yes1

Sujet: Proto-oncogene tyrosine-protein kinase Yes is an enzyme that in humans is encoded by the YES1 gene. This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. YES1 has been shown to interact with Janus kinase 2, CTNND1, RPL10 and Occludin.

Synonyms: c Yes antibody|Cellular Yes 1 protein antibody|Cellular Yes1 protein antibody|HsT441 antibody|P61 YES antibody|p61-Yes antibody|Proto oncogene tyrosine protein kinase YES antibody|Proto-oncogene c-Yes antibody|Proto-oncogene tyrosine-protein kinase Yes antibody| Tyrosine-protein kinase Yes antibody|v yes 1 Yamaguchi sarcoma viral oncogene homolog 1 antibody|Viral oncogene yes 1 homolog 1 antibody|Viral oncogene yes1 homolog 1 antibody| Yamaguchi sarcoma oncogene antibody|Yes 1 antibody|Yes antibody|YES_HUMAN antibody|YES1 antibody

ID gène: 7525

UniProt: P07947

Pathways: CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling