TGFA anticorps (C-Term)

N° du produit ABIN3042615

Détail du produit anti-TGFA anticorps

Antigène: TGFA (Transforming Growth Factor, alpha (TGFA))

Épitope: AA 73-89, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TGFA est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Protransforming growth factor alpha(TGFA) detection. Tested with WB in Human.

Séquence: CHSGYVGARC EHADLLA

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Protransforming growth factor alpha(TGFA) detection. Tested with WB in Human.
Gene Name: transforming growth factor, alpha
Protein Name: Protransforming growth factor alpha

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human TGF alpha(73-89aa CHSGYVGARCEHADLLA), different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Références pour anticorps anti-TGFA (ABIN3042615)

Li, Pan, Qiu: "Imbalances of Th17 and Treg cells and their respective cytokines in COPD patients by disease stage." dans: International journal of clinical and experimental medicine, Vol. 7, Issue 12, pp. 5324-9, (2015) (PubMed).

Ruan, Xu, Li, Zhu, Pang, Wang, Cai, He, Yao, Ruan, Xu, Pan: "Induced autologous stem cell transplantation for treatment of rabbit renal interstitial fibrosis." dans: PLoS ONE, Vol. 8, Issue 12, pp. e83507, (2013) (PubMed).

Zhang, Chen, Qi, Wang, Xiao, Zhu: "Inhibition of calcium-calmodulin-dependent kinase II suppresses cardiac fibroblast proliferation and extracellular matrix secretion." dans: Journal of cardiovascular pharmacology, Vol. 55, Issue 1, pp. 96-105, (2010) (PubMed).

Détails sur TGFA

Antigène: TGFA (Transforming Growth Factor, alpha (TGFA))

Autre désignation: TGFA (TGFA Produits)

Synonymes: anticorps TFGA, anticorps LOC100009482, anticorps TGF alpha, anticorps TGFA, anticorps wa-1, anticorps wa1, anticorps RATTGFAA, anticorps TGFAA, anticorps NV15606, anticorps si:ch211-10e8.7, anticorps transforming growth factor alpha, anticorps transforming growth factor alpha L homeolog, anticorps transforming growth factor-alpha, anticorps transforming growth factor, alpha, anticorps TGFA, anticorps TGF-A, anticorps Tgfa, anticorps tgfa.L, anticorps LOC100121300, anticorps LOC100009150, anticorps tgfa

Sujet: Transforming growth factor alpha(TGF-alpha) is upregulated in some human cancers. It is produced in macrophages, brain cells, and keratinocytes, and induces epithelial development. It is closely related to EGF, and can also bind to the EGF receptor with similar effects . TGFalpha stimulates neural cell proliferation in the adult injured brain. TGFalpha was cited in the 2001 NIH Stem Cell report to the U.S. Congress as promising evidence for the ability of adult stem cells to restore function in neurodegenerative disorders.

Synonyms: EGF like TGF antibody|EGF-like TGF antibody|ETGF antibody|TFGA antibody|TGF A antibody|TGF type 1 antibody|TGF-alpha antibody|TGFA antibody|TGFA_HUMAN antibody|Transforming growth factor alpha antibody|Transforming growth factor alpha precursor antibody|Wa1 antibody|Waved 1 antibody

UniProt: P01135

Pathways: Signalisation NF-kappaB, Signalisation RTK, EGFR Signaling Pathway