IL-10 anticorps (N-Term)
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- Antigène Voir toutes IL-10 (IL10) Anticorps
- IL-10 (IL10) (Interleukin 10 (IL10))
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Épitope
- AA 46-60, N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IL-10 est non-conjugé
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Application
- Western Blotting (WB)
- Fonction
- Rabbit IgG polyclonal antibody for Interleukin-10(IL10) detection. Tested with WB in Human.
- Séquence
- DAFSRVKTFF QMKDQ
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
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Rabbit IgG polyclonal antibody for Interleukin-10(IL10) detection. Tested with WB in Human.
Gene Name: interleukin 10
Protein Name: Interleukin-10(IL-10) - Purification
- Immunogen affinity purified.
- Immunogène
- A synthetic peptide corresponding to a sequence at the N-terminus of human IL10(46-60aa DAFSRVKTFFQMKDQ).
- Isotype
- IgG
- Top Product
- Discover our top product IL10 Anticorps primaire
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- Indications d'application
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Agent conservateur
- Thimerosal (Merthiolate), Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Date de péremption
- 12 months
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Re-polarizing Myeloid-derived Suppressor Cells (MDSCs) with Cationic Polymers for Cancer Immunotherapy." dans: Scientific reports, Vol. 6, pp. 24506, (2017) (PubMed).
: "Women with recurrent spontaneous abortion have decreased 25(OH) vitamin D and VDR at the fetal-maternal interface." dans: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, Vol. 50, Issue 11, pp. e6527, (2017) (PubMed).
: "Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats." dans: Nutrients, Vol. 7, Issue 6, pp. 4829-50, (2016) (PubMed).
: "Pentoxifylline inhibits pulmonary inflammation induced by infrarenal aorticcross-clamping dependent of adenosine receptor A2A." dans: American journal of translational research, Vol. 8, Issue 5, pp. 2210-21, (2016) (PubMed).
: "Evaluation of the probiotic properties of new Lactobacillus and Bifidobacterium strains and their in vitro effect." dans: Applied microbiology and biotechnology, Vol. 99, Issue 13, pp. 5613-26, (2015) (PubMed).
: "IL-10 and IL-1? mediate neuropathic-pain like behavior in the ventrolateral orbital cortex." dans: Neurochemical research, Vol. 40, Issue 4, pp. 733-9, (2015) (PubMed).
: "Inhibition of Tumor Growth and Immunomodulatory Effects of Flavonoids and Scutebarbatines of Scutellaria barbata D. Don in Lewis-Bearing C57BL/6 Mice." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 630760, (2015) (PubMed).
: "Putative role of ischemic postconditioning in a rat model of limb ischemia and reperfusion: involvement of hypoxia-inducible factor-1? expression." dans: Brazilian journal of medical and biological research = Revista brasileira de pesquisas me?dicas e biolo?gicas / Sociedade Brasileira de Biofi?sica ... [et al.], Vol. 47, Issue 9, pp. 738-45, (2014) (PubMed).
: "Targeted depletion of tumour-associated macrophages by an alendronate-glucomannan conjugate for cancer immunotherapy." dans: Biomaterials, Vol. 35, Issue 38, pp. 10046-57, (2014) (PubMed).
: "Exogenous interleukin-10 alleviates allergic inflammation but inhibits local interleukin-10 expression in a mouse allergic rhinitis model." dans: BMC immunology, Vol. 15, pp. 9, (2014) (PubMed).
: "Protective roles of quercetin in acute myocardial ischemia and reperfusion injury in rats." dans: Molecular biology reports, Vol. 39, Issue 12, pp. 11005-9, (2012) (PubMed).
: "Anti-tumor immune responses of tumor-associated macrophages via toll-like receptor 4 triggered by cationic polymers." dans: Biomaterials, Vol. 34, Issue 3, pp. 746-55, (2012) (PubMed).
: "Targeted delivery of oligonucleotides into tumor-associated macrophages for cancer immunotherapy." dans: Journal of controlled release : official journal of the Controlled Release Society, Vol. 158, Issue 2, pp. 286-92, (2012) (PubMed).
: "Interleukin-10 of red nucleus plays anti-allodynia effect in neuropathic pain rats with spared nerve injury." dans: Neurochemical research, Vol. 37, Issue 8, pp. 1811-9, (2012) (PubMed).
: "Additive effects of ulinastatin and docetaxel on growth of breast cancer xenograft in nude mice and expression of PGE2, IL-10, and IL-2 in primary breast cancer cells." dans: Cancer biotherapy & radiopharmaceuticals, Vol. 27, Issue 4, pp. 252-8, (2012) (PubMed).
: "Increased IL-10 mRNA expression in tumor-associated macrophage correlated with late stage of lung cancer." dans: Journal of experimental & clinical cancer research : CR, Vol. 30, pp. 62, (2011) (PubMed).
: "Effects of penehyclidine hydrochloride in small intestinal damage caused by limb ischemia-reperfusion." dans: World journal of gastroenterology, Vol. 17, Issue 2, pp. 254-9, (2011) (PubMed).
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Re-polarizing Myeloid-derived Suppressor Cells (MDSCs) with Cationic Polymers for Cancer Immunotherapy." dans: Scientific reports, Vol. 6, pp. 24506, (2017) (PubMed).
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- Antigène
- IL-10 (IL10) (Interleukin 10 (IL10))
- Autre désignation
- IL10 (IL10 Produits)
- Synonymes
- anticorps CSIF, anticorps GVHDS, anticorps IL-10, anticorps IL10A, anticorps TGIF, anticorps Il-10, anticorps IL10X, anticorps interleukin 10, anticorps IL10, anticorps Il10
- Sujet
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Interleukin-10(IL-10 or IL10), also known as human cytokine synthesis inhibitory factor(CSIF), is an anti-inflammatory cytokine. In humans IL-10 is encoded by the IL10 gene. It is capable of inhibiting synthesis of pro-inflammatory cytokines like IFN-gamma, IL-2, IL-3, TNFalpha and GM-CSF made by cells such as macrophages and regulatory T-cells.IL-10 also displays potent abilities to suppress the antigen presentation capacity of antigen presenting cells. Kim et al.(1992) showed that the mouse Il 10 gene contains 5 exons and spans about 5.2 kb of genomic DNA. Eskdale et al.(1997) mapped the IL10 gene to the junction between 1q31 and 1q32.
Synonyms: CSIF antibody|Cytokine Synthesis Inhibitory Factor antibody|GVHDS antibody|IL 10 antibody|IL-10 antibody|IL10 antibody|IL10A antibody|Interleukin 10 antibody|Interleukin-10 antibody|Interleukin10 antibody|MGC126450 antibody|MGC126451 antibody|T-cell growth inhibitory factor antibody|TGIF antibody - UniProt
- P22301
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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