Peroxiredoxin 2 anticorps (C-Term)

N° du produit ABIN3043026

Détail du produit anti-Peroxiredoxin 2 anticorps

Antigène: Peroxiredoxin 2 (PRDX2)

Épitope: AA 181-198, C-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Peroxiredoxin 2 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Peroxiredoxin-2(PRDX2) detection. Tested with WB in Human,Mouse,Rat.

Séquence: DTIKPNVDDS KEYFSKHN

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Peroxiredoxin-2(PRDX2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: peroxiredoxin 2
Protein Name: Peroxiredoxin-2

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Peroxiredoxin 2(181-198aa DTIKPNVDDSKEYFSKHN), identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Références pour anticorps anti-Peroxiredoxin 2 (ABIN3043026)

You, Zhang, Li, Li, Li, Li, Zhu, Peng, Sun: "Cloning and molecular characterization of phospholipase D (PLD) delta gene from longan (Dimocarpus longan Lour.)." dans: Molecular biology reports, Vol. 41, Issue 7, pp. 4351-60, (2014) (PubMed).

Détails sur Peroxiredoxin 2

Antigène: Peroxiredoxin 2 (PRDX2)

Autre désignation: PRDX2 (PRDX2 Produits)

Synonymes: anticorps NKEF-B, anticorps NKEFB, anticorps PRP, anticorps PRX2, anticorps PRXII, anticorps PTX1, anticorps TDPX1, anticorps TPX1, anticorps TSA, anticorps AL022839, anticorps Band-8, anticorps NkefB, anticorps PrxII, anticorps TDX1, anticorps TPx, anticorps TPx-B, anticorps TR, anticorps Tdpx1, anticorps Torin, anticorps nkefb, anticorps prx-2, anticorps prx2, anticorps prxii, anticorps tdpx1, anticorps tpx1, anticorps peroxiredoxin 2, anticorps peroxiredoxin 2 L homeolog, anticorps PRDX2, anticorps Prdx2, anticorps prdx2.L

Sujet: PRDX2(peroxiredoxin 2) also known as NKEFB, PRP, PRX2, PRXII or TPX1, is a protein that in humans is encoded by the PRDX2 gene. This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The Prdx2 -/- mice were healthy in appearance and fertile. Choi et al.(2005) demonstrated that PRDX2 is a negative regulator of PDGF signaling. Prx II deficiency results in increased production of peroxide, enhanced activation of PDGF receptor and phospholipase C-gamma-1, and subsequently increased cell proliferation and migration in response to PDGF. PRX2 accounted for about half of the thioredoxin activity in parasite extracts, and PRX2 expression was increased in the presence of chloroquine, regardless of P. falciparum strain susceptibility to the drug.

Synonyms: MGC4104 antibody|Natural killer cell enhancing factor B antibody|Natural killer cell-enhancing factor B antibody|Natural Killer Enhancing Factor B antibody|NKEF B antibody|NKEF-B antibody|NKEFB antibody|Peroxiredoxin-2 antibody|PRDX 2 antibody|PRDX2 antibody|PRDX2_HUMAN antibody|PrP antibody|PRX2 antibody|PRXII antibody|TDPX1 antibody|Thiol Specific Antioxidant 1 antibody|Thiol specific antioxidant protein antibody|Thiol-specific antioxidant protein antibody|Thioredoxin Dependent Peroxide Reductase 1 antibody|Thioredoxin peroxidase 1 antibody|Thioredoxin-dependent peroxide reductase 1 antibody|Torin antibody|TPX1 antibody|TSA antibody

UniProt: P32119