IL2RG anticorps (Middle Region)

N° du produit ABIN3043145

Détail du produit anti-IL2RG anticorps

Antigène: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Épitope: AA 88-102, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL2RG est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Cytokine receptor common subunit gamma(IL2RG) detection. Tested with WB in Human.

Séquence: HYWYKNSDND KVQKC

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Cytokine receptor common subunit gamma(IL2RG) detection. Tested with WB in Human.
Gene Name: interleukin 2 receptor, gamma
Protein Name: Cytokine receptor common subunit gamma

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human IL2 Receptor gamma(88-102aa HYWYKNSDNDKVQKC).

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur IL2RG

Antigène: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Autre désignation: IL2RG (IL2RG Produits)

Synonymes: anticorps Ab2-183, anticorps Cd132, anticorps CD132, anticorps CIDX, anticorps IL-2RG, anticorps IMD4, anticorps P64, anticorps SCIDX, anticorps SCIDX1, anticorps [g]c, anticorps gamma(c), anticorps gc, anticorps interleukin 2 receptor subunit gamma, anticorps interleukin 2 receptor subunit gamma L homeolog, anticorps interleukin 2 receptor, gamma chain, anticorps IL2RG, anticorps il2rg.L, anticorps Il2rg

Sujet: IL2RG(INTERLEUKIN 2 RECEPTOR, GAMMA),also known as Common gamma chain or CD132, is a cytokine receptor sub-unit that is common to the receptor complexes for at least six different interleukin receptors:IL-2, IL-4, IL-7, IL-9, IL-15 and interleukin-21 receptor. IL2RG is a member of the type I cytokine receptor family expressed on most lymphocyte(white blood cell) populations, and its gene is found on the X-chromosome of mammals. By fluorescence in situ hybridization and PCR amplification of somatic cell hybrid DNAs, The IL2RG gene is mapped to Xq13.1. The IL2RG gene contains 8 exons and spans approximately 4.2 kb. And the gamma chain is an indispensable component of the functional IL2 receptor. Lymphocytes expressing the common gamma chain can form functional receptors for these cytokine proteins, which transmit signals from one cell to another and direct programs of cellular differentiation. The sharing of the gamma subunit by several receptors explains why humans and mice that lack IL2 entirely show milder symptoms than those with IL2RG deficiency.

Synonyms: CD132 antibody|common cytokine receptor gamma chain antibody|Cytokine receptor common subunit gamma antibody|Gamma C antibody|gamma(c) antibody|gammaC antibody|IL-2 receptor subunit gamma antibody|IL-2R gamma chain antibody|IL-2R subunit gamma antibody|IL-2RG antibody|Il2rg antibody|IL2RG_HUMAN antibody|IMD4 antibody|interleukin 2 receptor, gamma antibody|Interleukin-2 receptor subunit gamma antibody|p64 antibody|SCIDX antibody|SCIDX1 antibody

UniProt: P31785

Pathways: Signalistation JAK/STAT, Growth Factor Binding