TRPM8 anticorps (C-Term)

N° du produit ABIN3043495

Détail du produit anti-TRPM8 anticorps

Antigène: TRPM8 (Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8))

Épitope: AA 1068-1104, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRPM8 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Transient receptor potential cation channel subfamily M member 8(TRPM8) detection. Tested with WB in Human.

Séquence: NTKANDTSEE MRHRFRQLDT KLNDLKGLLK EIANKIK

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Transient receptor potential cation channel subfamily M member 8(TRPM8) detection. Tested with WB in Human.
Gene Name: transient receptor potential cation channel, subfamily M, member 8
Protein Name: Transient receptor potential cation channel subfamily M member 8

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human TRPM8 (1068-1104aa NTKANDTSEEMRHRFRQLDTKLNDLKGLLKEIANKIK), different from the related mouse sequence by four amino acids, and from the related rat sequence by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur TRPM8

Antigène: TRPM8 (Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8))

Autre désignation: TRPM8 (TRPM8 Produits)

Synonymes: anticorps TRPM8, anticorps trpp8, anticorps ltrpc6, anticorps trpm8b, anticorps LTRPC6, anticorps TRPP8, anticorps CMR1, anticorps LTrpC-6, anticorps Trp-p8, anticorps transient receptor potential cation channel subfamily M member 8, anticorps transient receptor potential cation channel subfamily M member 8b L homeolog, anticorps transient receptor potential cation channel, subfamily M, member 8, anticorps TRPM8, anticorps trpm8b.L, anticorps Trpm8

Sujet: Transient receptor potential cation channel subfamily M member 8 (TRPM8), also known as the cold and menthol receptor 1 (CMR1), is a protein that in humans is encoded by the TRPM8 gene. TRPM8 is an ion channel, upon activation it allows the entry of Na+ (sodium) and Ca2+ (calcium) ions to the cell that leads to depolarization and the generation of an action potential. The signal is conducted from primary afferents (type C- and A-delta) eventually leading to the sensation of cold and cold pain. The TRPM8 protein is expressed in sensory neurons, and it is activated by cold temperatures and cooling agents, such as menthol and icilin whereas WS-12 and CPS-369 are the most selective agonist of TRPM8.

Synonyms: Long transient receptor potential channel 6 antibody|LTrpC-6 antibody|LTrpC6 antibody|MGC2849 antibody|Short form of the TRPM8 cationic channel antibody|Transient receptor potential cation channel subfamily M member 8 antibody|Transient receptor potential p8 antibody|transient receptor potential-p8 antibody|Trp p8 antibody|Trp-p8 antibody|Trpm8 antibody|TRPM8_HUMAN antibody|TRPP8 antibody

ID gène: 79054

UniProt: Q7Z2W7