Acetylcholinesterase anticorps (C-Term)

N° du produit ABIN3043517

Détail du produit anti-Acetylcholinesterase anticorps

Antigène: Acetylcholinesterase (AChE)

Épitope: AA 592-614, C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Acetylcholinesterase est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Acetylcholinesterase(ACHE) detection. Tested with WB in Human,Mouse,Rat.

Séquence: SSYMVHWKNQ FDHYSKQDRC SDL

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Acetylcholinesterase(ACHE) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: acetylcholinesterase (Yt blood group)
Protein Name: Acetylcholinesterase

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human ACHE (592-614aa SSYMVHWKNQFDHYSKQDRCSDL), different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for ACHE is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur Acetylcholinesterase

Antigène: Acetylcholinesterase (AChE)

Autre désignation: ACHE (AChE Produits)

Synonymes: anticorps ACEE, anticorps ARACHE, anticorps N-ACHE, anticorps YT, anticorps Ache, anticorps GB14873, anticorps zgc:92550, anticorps ACE, anticorps Dsim\\GD20515, anticorps GD20515, anticorps dsim_GLEANR_4292, anticorps ache, anticorps mE1a, anticorps mE1b, anticorps mE1c, anticorps mE1c-long, anticorps mE1d, anticorps mE1d', anticorps mE1e, anticorps arache, anticorps n-ache, anticorps acetylcholinesterase (Cartwright blood group), anticorps acetylcholinesterase 2, anticorps acetylcholinesterase, anticorps Acetylcholine esterase, anticorps acetylcholinesterase (Cartwright blood group) L homeolog, anticorps collagen type I alpha 2 chain, anticorps ACHE, anticorps AChE-2, anticorps Ache, anticorps ache, anticorps Dsim\Ace, anticorps ache.L, anticorps COL1A2, anticorps ACE-1

Sujet: ACHE is also known as Acetylcholinesterase. And Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally.

Synonyms: ACEE antibody|ACES_HUMAN antibody|Acetylcholine acetylhydrolase antibody| Acetylcholinesterase antibody|Acetylcholinesterase YT blood group antibody|ACHE antibody| ACHE protein antibody|Apoptosis related acetylcholinesterase antibody|ARACHE antibody|N ACHE antibody|N-ACHE antibody|YT antibody|Yt blood group antibody

ID gène: 43

UniProt: P22303

Pathways: Skeletal Muscle Fiber Development