ABCG5 anticorps (N-Term)

N° du produit ABIN3043776

Détail du produit anti-ABCG5 anticorps

Antigène: ABCG5 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))

Épitope: AA 197-221, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCG5 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family G member 5(ABCG5) detection. Tested with WB in Human.

Séquence: ERRRVSIAAQ LLQDPKVMLF DEPTT

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family G member 5(ABCG5) detection. Tested with WB in Human.
Gene Name: ATP-binding cassette, sub-family G (WHITE), member 5
Protein Name: ATP-binding cassette sub-family G member 5

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human ABCG5 (197-221aa ERRRVSIAAQLLQDPKVMLFDEPTT), different from the related mouse and rat sequences by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human , The detection limit for ABCG5 is approximately 0.1 ng/lane under reducing conditions.
Notes: WB: The detection limit for ABCG5 is approximately 0.1 ng/lane under reducing conditions. Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur ABCG5

Antigène: ABCG5 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))

Autre désignation: ABCG5 (ABCG5 Produits)

Synonymes: anticorps DDBDRAFT_0205617, anticorps DDBDRAFT_0215344, anticorps DDB_0205617, anticorps DDB_0215344, anticorps STSL, anticorps AW112016, anticorps cmp, anticorps sterolin-1, anticorps trac, anticorps ATP binding cassette subfamily G member 5, anticorps ATP-binding cassette, sub-family G (WHITE), member 5, anticorps ABC transporter G family protein, anticorps ABCG5, anticorps abcg5, anticorps abcG5, anticorps Abcg5

Sujet: ABCG5 (Atp-binding cassette, subfamily g, member 5) also known as STEROLIN 1, is a protein that in humans is encoded by the ABCG5 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. The ABCG5 gene contains 13 exons and spans about 28 kb. The ABCG5 gene is mapped on 2p21. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. Small (2003) reviewed the role of ABC transporters in secretion of cholesterol from liver into bile, particularly the role of ABCG5/ABCG8. The ABCG5 and ABCG8 genes are an example of closely neighboring genes in a head-to-head orientation that, when mutated, cause the same phenotype.

Synonyms: ABCG5 antibody|ABCG5_HUMAN antibody|ATP binding cassette sub family G (WHITE) member 5 (sterolin 1) antibody|ATP binding cassette sub family G member 5 antibody|ATP-binding cassette sub-family G member 5 antibody|Sterolin 1 antibody|Sterolin-1 antibody|STSL antibody

ID gène: 64240

UniProt: Q9H222

Pathways: Lipid Metabolism