ABCG5 anticorps (AA 306-367)
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- Antigène Voir toutes ABCG5 Anticorps
- ABCG5 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))
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Épitope
- AA 306-367
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp ABCG5 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human ABCG5 (AA: 306-367) expressed in E. coli.
- Clone
- 1B5E10
- Isotype
- IgG1
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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ATP-binding cassette transporter G5 and G8 polymorphisms and several environmental factors with serum lipid levels." dans: PLoS ONE, Vol. 7, Issue 5, pp. e37972, (2012) (PubMed).
: "Bile acids stimulate ATP hydrolysis in the purified cholesterol transporter ABCG5/G8." dans: Biochemistry, Vol. 49, Issue 16, pp. 3403-11, (2010) (PubMed).
: "
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ATP-binding cassette transporter G5 and G8 polymorphisms and several environmental factors with serum lipid levels." dans: PLoS ONE, Vol. 7, Issue 5, pp. e37972, (2012) (PubMed).
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- Antigène
- ABCG5 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))
- Autre désignation
- ABCG5 (ABCG5 Produits)
- Synonymes
- anticorps DDBDRAFT_0205617, anticorps DDBDRAFT_0215344, anticorps DDB_0205617, anticorps DDB_0215344, anticorps STSL, anticorps AW112016, anticorps cmp, anticorps sterolin-1, anticorps trac, anticorps ATP binding cassette subfamily G member 5, anticorps ATP-binding cassette, sub-family G (WHITE), member 5, anticorps ABC transporter G family protein, anticorps ABCG5, anticorps abcg5, anticorps abcG5, anticorps Abcg5
- Sujet
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Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. , ,
Aliases: STSL
- Poids moléculaire
- 72.5 kDa
- ID gène
- 64240
- HGNC
- 64240
- Pathways
- Lipid Metabolism
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