HSPE1 anticorps (C-Term)

N° du produit ABIN3044176

Détail du produit anti-HSPE1 anticorps

Antigène: HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))

Épitope: AA 81-102, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSPE1 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for 10 kDa heat shock protein, mitochondrial(HSPE1) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.

Séquence: VVLDDKDYFL FRDGDILGKY VD

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for 10 kDa heat shock protein, mitochondrial(HSPE1) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: heat shock 10 kDa protein 1(chaperonin 10)
Protein Name: 10 kDa heat shock protein, mitochondrial(Hsp10)

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Cpn10(81-102aa VVLDDKDYFLFRDGDILGKYVD), different from the related rat and mouse sequences by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur HSPE1

Antigène: HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))

Autre désignation: HSPE1 (HSPE1 Produits)

Synonymes: anticorps CPN10, anticorps EPF, anticorps GROES, anticorps HSP10, anticorps groS, anticorps Cpn10, anticorps cpn10, anticorps zgc:86747, anticorps hspe1, anticorps MGC89647, anticorps HSPE1, anticorps MITOCHONDRIAL CHAPERONIN 10, anticorps T15D22.2, anticorps T15D22_2, anticorps chaperonin 10, anticorps Dmel\\CG11267, anticorps Hsp10, anticorps anon-WO0118547.175, anticorps hsp10, anticorps crpB, anticorps chpS, anticorps 10kDa, anticorps mt-cpn10, anticorps heat shock protein family E (Hsp10) member 1, anticorps molecular chaperone GroES, anticorps chaperonin 10 kDa, anticorps chaperonin, 10 kDa, anticorps chaperonin-10 kDa, anticorps heat shock protein family E member 1, anticorps heat shock 10 protein 1, anticorps heat shock protein family E (Hsp10) member 1 L homeolog, anticorps heat shock 10kDa protein 1 (chaperonin 10) pseudogene, anticorps 10 kd chaperonin, anticorps chaperonin 10, anticorps Hsp10p, anticorps co-chaperonin 10, mitochondrial, anticorps CG11267 gene product from transcript CG11267-RA, anticorps co-chaperonin GroES, anticorps mitochondrial heat shock protein Hsp10 (predicted), anticorps chaperonin GroS, anticorps Hsp10 10 kDa chaperonin GROES, anticorps mitochondrial heat shock protein Hsp10, anticorps heat shock protein 10, anticorps heat shock protein 1 (chaperonin 10), anticorps heat shock 10kDa protein 1 (chaperonin 10), anticorps HSPE1, anticorps groES, anticorps groES2, anticorps TP01_0190, anticorps Cag_1167, anticorps Bm1_56470, anticorps Hspe1, anticorps hspe1, anticorps hspe1.L, anticorps LOC452179, anticorps Cpn10, anticorps CPN10, anticorps HSP10, anticorps CG11267, anticorps hsp10, anticorps groS

Sujet: HSPE1(heat shock 10 kDa protein 1(chaperonin 10)), also called CPN10, GROES, CHAPERONIN 10 HOMOLOG, cpn10 HOMOLOG or HSP10, is a protein that in humans is encoded by the HSPE1 gene. GroES is a heptameric ring of identical 10.4-kD subunits that binds to each end of GroEL to form a symmetric, functional heterodimer. The HSP10 gene consists of 4 exons. The HSPE1 gene is mapped to 2q33.1. The transcriptional activity of the promoter fragment in the HSP60 direction is approximately twice that in the HSP10 direction under normal growth conditions, upon heat shock, promoter activity in either direction increased by a factor of approximately 12. Mutational drifts performed in vitro with 4 different enzymes indicated the GroES overexpression doubled the number of accumulating mutations, and promoted the folding of enzyme variants carrying mutations in the protein core and/or mutations with higher destabilizing effects.

Synonyms: 10 kDa chaperonin antibody|10 kDa heat shock protein mitochondrial antibody|10 kDa heat shock protein, mitochondrial antibody|CH10_HUMAN antibody|Chaperonin 10 antibody|Cpn 10 antibody|CPN10 antibody|Early pregnancy factor antibody|Early-pregnancy factor antibody|EPF antibody|GROES antibody|Heat shock 10kD protein 1 antibody|Heat shock 10kD protein 1 chaperonin 10 antibody|Heat shock 10 kDa protein 1 antibody|Heat shock 10 kDa protein 1 chaperonin 10 antibody|HSP 10 antibody|HSP10 antibody|HSPE 1 antibody|HSPE1 antibody

UniProt: P61604

Pathways: Positive Regulation of Endopeptidase Activity