APOA1 anticorps (AA 25-264)
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- Antigène Voir toutes APOA1 Anticorps
- APOA1 (Apolipoprotein A-I (APOA1))
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Épitope
- AA 25-264
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp APOA1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Fonction
- Rabbit IgG polyclonal antibody for Apolipoprotein A-I(APOA1) detection. Tested with WB, IHC-P in Mouse.
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
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Rabbit IgG polyclonal antibody for Apolipoprotein A-I(APOA1) detection. Tested with WB, IHC-P in Mouse.
Gene Name: apolipoprotein A-I
Protein Name: Apolipoprotein A-I - Purification
- Immunogen affinity purified.
- Immunogène
- E. coli-derived mouse APOA1 recombinant protein (Position: D25-Q264). Mouse APOA1 shares 64% and 68.6% amino acid (aa) sequence identity with human and rat APOA1, respectively.
- Isotype
- IgG
- Top Product
- Discover our top product APOA1 Anticorps primaire
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- Indications d'application
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Antigène
- APOA1 (Apolipoprotein A-I (APOA1))
- Autre désignation
- APOA1 (APOA1 Produits)
- Synonymes
- anticorps Alp-1, anticorps Apoa-1, anticorps Brp-14, anticorps Ltw-1, anticorps Lvtw-1, anticorps Sep-1, anticorps Sep-2, anticorps Sep2, anticorps apoA-I, anticorps apoa, anticorps apoa1, anticorps cb49, anticorps wu:fb33f01, anticorps zgc:103718, anticorps MGC64335, anticorps MGC89745, anticorps Apo-AI, anticorps ApoA-I, anticorps APOA1, anticorps LOC100136573, anticorps apoa-i, anticorps ApoAI, anticorps apolipoprotein A1, anticorps apolipoprotein A-I, anticorps apolipoprotein A-Ia, anticorps apolipoprotein A-I S homeolog, anticorps apolipoprotein A4, anticorps APOA1, anticorps Apoa1, anticorps apoa1a, anticorps apoa1.S, anticorps apoa1, anticorps LOC100136573, anticorps apoa-i, anticorps apoa4
- Sujet
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Apolipoprotein A-1, also known as APOA1, is a human protein with a specific role in lipid metabolism. It binds to lipopolysaccharide or endotoxin, and has a major role in the anti-endotoxin function of HDL. The gene is mapped to 11q23. And it is a single polypeptide chain with 243 amino acid residues of known primary amino acid sequence. The ApoA-I protein promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. ApoA-I is also isolated as a prostacyclin (PGI2) stabilizing factor, and thus may have an anticlotting effect. Defects in the gene encoding it are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Additionally, ApoA-I overexpression promotes macrophage-specific reverse cholesterol transport.
Synonyms: Apo AI antibody|Apo-AI antibody|ApoA I antibody|ApoA-I antibody|APOA1 antibody|APOA1/APOC3 fusion gene antibody|APOA1_HUMAN antibody| Apolipoprotein A I precursor antibody|Apolipoprotein A-I(1-242) antibody|Apolipoprotein A1 antibody|Apolipoprotein AI antibody| Apolipoprotein of high density lipoprotein antibody|ApolipoproteinAI antibody|Brp14 antibody|Ltw1 antibody|Lvtw1 antibody|MGC117399 antibody|Sep1 antibody|Sep2 antibody - ID gène
- 11806
- UniProt
- Q00623
- Pathways
- Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
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