Notch1 anticorps (PE)

N° du produit ABIN306235

Détail du produit anti-Notch1 anticorps (PE)

Antigène: Notch1 (NOTCH1) (Notch 1 (NOTCH1))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Notch1 est conjugé à/à la PE

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: Specific for mouse Notch1, a single transmembrane receptor which is expressed in a range of cells including hematopoietic cells in mouse fetal liver, adult thymus and bone marrow. Notch1 plays a role in embryonic development and tissue homeostasis in the adult. Recent work has suggested a further role for this receptor in the regulation of lymphopoiesis and myelopoiesis. Following ligand binding, Notch1 is cleaved in the transmembrane domain, releasing the Notch intracellular domain (NICD) to translocate to the nucleus, where it plays a role in the modulation of gene expression.

Purification: Protein G purified

Immunogène: Synthetic peptide corresponding to cdc10-NCR region within mouse Notch1.

Type of Immunogen: Synthetic peptide

Isotype: IgG1

Information d'application

Indications d'application: Approved: Flo (1:1 - 1:10), IHC, IHC-Fr, WB

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Membrane permeabilization is required for this application.

Commentaires:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Distilled Water.

Concentration: Lot specific

Buffer: Lyophilized, PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur Notch1

Antigène: Notch1 (NOTCH1) (Notch 1 (NOTCH1))

Autre désignation: NOTCH1 (NOTCH1 Produits)

Synonymes: anticorps notch1, anticorps NOTCH1, anticorps hn1, anticorps tan1, anticorps notch, anticorps xotch, anticorps xnotch, anticorps notch-1, anticorps xnotch1, anticorps TAN1, anticorps hN1, anticorps 9930111A19Rik, anticorps Mis6, anticorps N1, anticorps Tan1, anticorps lin-12, anticorps NOTCH, anticorps Xotch, anticorps notch1-a, anticorps notch 1, anticorps fibropellin-1, anticorps Notch homolog 1, translocation-associated (Drosophila), anticorps Notch homolog 1, translocation-associated, anticorps notch 1 S homeolog, anticorps notch1, anticorps LOC100631526, anticorps NOTCH1, anticorps Notch1, anticorps notch1.S

Sujet: Name/Gene ID: NOTCH1

Synonyms: NOTCH1, Notch 1, TAN1

ID gène: 4851

UniProt: P46531

Pathways: Signalisation Notch, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development