c-MYC anticorps

N° du produit ABIN306633

Cet anticorps anti-c-MYC Monoclonal Souris (Clone 33) (ABIN306633) détecte spécifiquement c-MYC dans WB, IHC et IP. L’anticorps est réactif avec des échantillons de Humain, Souris et Avian.

Aperçu rapide pour c-MYC anticorps (ABIN306633)

Antigène: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Reactivité: Humain, Souris, Avian

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp c-MYC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: 33

Détail du produit anti-c-MYC anticorps

Fonction: Mouse anti Human myc

Attributs du produit: Human c-myc belongs to a family of 5 myc oncogenes. Amplification of c-myc has been found in several types of human tumors including breast and colon carcinomas. Induction of c-myc in cells grown in the appropriate growth factors or co-expression with survival genes, such as bcl-2 causes cell proliferation. In the abscence of these factors, c-myc expression causes cell death. c-myc gene gives rise to at least two nuclear phosphoproteins of 64 kDa and 67 kDa, the unphosphorylated form is 49 kDa.

Purification: Protein A/G Chromatography

Isotype: IgG1

Information d'application

Indications d'application: Application: Western Blot, Immunoprecipitation (both with and without SDS), Immunofluorescence on frozen sections (c-Myc is a labile protein, therefore preotease inhibitors should be used at all times).

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur c-MYC

Antigène: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Autre désignation: c-myc

Sujet: Cmyc, Myc proto-oncogene protein, transcription factor p64

Poids moléculaire: 64kDa,67kDa,49kDa

UniProt: P01106, P01108, P09416

Pathways: Signalisation p53, Cycle Cellulaire, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, L'effet Warburg