Kv1.4 anticorps (N-Term)

N° du produit ABIN306872

Détail du produit anti-Kv1.4 anticorps

Antigène: Kv1.4 (KCNA4) (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 4 (KCNA4))

Épitope: N-Term

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kv1.4 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Voltage-Gated Potassium Channel, Kv1.4 isoform,The Kv1.4 potassium channel is a voltage-gated channel protein which belongs to the delayed rectifier class and to the Shaker potassium channel subfamily which includes Kv1.1, Kv1.2, Kv1.3 and Kv1.5. Potassium channels are mainly found in plasma membranes but are not generally distributed over the cell surface. Potassium channels catalyze the rapid permeation of potassium ions while rejecting biologically abundant potential competitors such as sodium, calcium and magnesium. Ion selectivity and high through put rate of potassium channels is accomplished by precise co-ordination of dehydrated potassium by the protein and multiple ion occupancy within the permeation pathway. All potassium channels carry out the formation of a transmembrane leak specific for potassium ions. Since cells almost universally maintain cytoplasmic potassium concentrations higher than those extracellularly, the opening of a potassium channel implies a negative ongoing change in electrical voltage across the cell membrane. This may result in termination of the action potential of electrically excitable cells including nerve, muscle and pancreatic beta cells. In nonexcitable cells, potassium channels play important roles in the cellular potassium recycling required for electrolyte balance effected by the renal epithelium.

Purification: Ammonium Sulfate Precipitation

Immunogène: Synthetic peptide derived from the N-terminus of the rat Kv1.4 potassium channel conjugated to KLH

Isotype: IgG

Information d'application

Indications d'application: This antibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Stockage

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur Kv1.4

Antigène: Kv1.4 (KCNA4) (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 4 (KCNA4))

Autre désignation: Kv1.4 Potassium Channel (NT) (KCNA4 Produits)

Synonymes: anticorps KV1.4, anticorps KCNA4, anticorps Kv1.4, anticorps DKFZp459N0126, anticorps KCHAN, anticorps Kv4, anticorps RHK1, anticorps RK3, anticorps HBK4, anticorps HK1, anticorps HPCN2, anticorps HUKII, anticorps KCNA4L, anticorps KCNA8, anticorps PCN2, anticorps potassium voltage-gated channel subfamily A member 4, anticorps potassium voltage-gated channel subfamily A member 4 S homeolog, anticorps potassium voltage-gated channel, shaker-related subfamily, member 4, anticorps KCNA4, anticorps LOC100622932, anticorps kcna4.S, anticorps Kcna4

UniProt: P22459