SLA anticorps
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- Antigène Voir toutes SLA Anticorps
- SLA (Src-Like-Adaptor (SLA))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SLA est non-conjugé
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Application
- Western Blotting (WB)
- Réactivité croisée
- Humain
- Attributs du produit
- Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins. Interacts with EPHA2, VAV1, LCP2 and PDGFRB. The C-terminal domain is essential for the homodimerization and the interaction with CBL. While the interaction with CBL is apparently mediated via the hydrophobic region of this domain, the highly charged region is apparently required for the homodimerization. Expressed in lung and fetal brain. Weakly expressed in heart, adult brain, placenta, liver, skeletal muscle, kidney and pancreas.
- Purification
- Ammonium Sulfate Precipitation
- Immunogène
- Synthetic peptide derived from the human SLAP1 protein.
- Isotype
- IgG
- Top Product
- Discover our top product SLA Anticorps primaire
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- Indications d'application
- Antibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.
- Restrictions
- For Research Use only
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- Buffer
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Antigène
- SLA (Src-Like-Adaptor (SLA))
- Autre désignation
- SLAP1 (Src-like Adaptor Protein-1) (SLA Produits)
- Synonymes
- anticorps SLA1, anticorps SLAP, anticorps src-like-adapter, anticorps SLA, anticorps Slap1, anticorps Slap, anticorps Slap-1, anticorps Src like adaptor, anticorps Src-like-adaptor, anticorps src-like adaptor, anticorps SLA, anticorps Sla
- UniProt
- Q13239
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