SLA anticorps

N° du produit ABIN306901

Détail du produit anti-SLA anticorps

Antigène: SLA (Src-Like-Adaptor (SLA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLA est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain

Attributs du produit: Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins. Interacts with EPHA2, VAV1, LCP2 and PDGFRB. The C-terminal domain is essential for the homodimerization and the interaction with CBL. While the interaction with CBL is apparently mediated via the hydrophobic region of this domain, the highly charged region is apparently required for the homodimerization. Expressed in lung and fetal brain. Weakly expressed in heart, adult brain, placenta, liver, skeletal muscle, kidney and pancreas.

Purification: Ammonium Sulfate Precipitation

Immunogène: Synthetic peptide derived from the human SLAP1 protein.

Isotype: IgG

Information d'application

Indications d'application: Antibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Stockage

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur SLA

Antigène: SLA (Src-Like-Adaptor (SLA))

Autre désignation: SLAP1 (Src-like Adaptor Protein-1) (SLA Produits)

Synonymes: anticorps SLA1, anticorps SLAP, anticorps src-like-adapter, anticorps SLA, anticorps Slap1, anticorps Slap, anticorps Slap-1, anticorps Src like adaptor, anticorps Src-like-adaptor, anticorps src-like adaptor, anticorps SLA, anticorps Sla

UniProt: Q13239