LTBR anticorps (Extracellular Domain) (PE)

N° du produit ABIN317402

Détail du produit anti-LTBR anticorps (PE)

Antigène: LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

Épitope: Extracellular Domain

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp LTBR est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Specificité: This antibody recognises lymphotoxin-beta receptor (LT beta R), a member of the tumour necrosis factor family. LT beta R is primarily expressed on stromal cells and fibroblasts and at lower levels on myeloid cell lines. Clone 5G11b specifically recognises surface expressed LT beta R. The clone is reported to be agonistic with respect to NF Kappa B activation, MIP-2 induction and IL-6 release (2). This product is routinely tested on mouse WEHI cells.

Attributs du produit: Synonyms: Tumor necrosis factor receptor 3, TNF-R3, Tumor necrosis factor C receptor, TNFCR,TNFRSF3, D12S370, Lymphotoxin-beta receptor, Tumor necrosis factor receptor superfamilymember 3, Tumor necrosis factor receptor type III, Tumor necrosis factor receptor 2-relatedprotein

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogène: Recombinant extracellular domain of LT beta R

Clone: 5G11b

Isotype: IgG2a

Information d'application

Indications d'application: Flow Cytometry: use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Reconstitute with 1.0 mL distilled water

Concentration: 0.05 mg/mL

Buffer: Phosphate buffered saline pH 7.4, 0.09 % Sodium Azide, 1 % Bovine Serum Albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody prior and following reconstitution at 2-8 °C. DO NOT FREEZE. This product is photosensitive and should be protected from light.
Shelf life: One year from despatch.

Date de péremption: 12 months

Détails sur LTBR

Antigène: LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

Autre désignation: LTBR / TNFR3 (LTBR Produits)

Synonymes: anticorps AI256028, anticorps CD18, anticorps LTbetaR, anticorps Ltar, anticorps TNF-R-III, anticorps TNFCR, anticorps TNFR-RP, anticorps TNFR2-RP, anticorps TNFRrp, anticorps Tnfbr, anticorps Tnfrsf3, anticorps D12S370, anticorps LT-BETA-R, anticorps TNFR3, anticorps TNFRSF3, anticorps lymphotoxin beta receptor, anticorps lymphotoxin B receptor, anticorps Ltbr, anticorps LTBR

Sujet: The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin alpha and lymphtoxin beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.Synonyms: D12S370, Lymphotoxin-beta receptor, TNF-R3, TNFCR, TNFRSF3, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, Tumor necrosis factor receptor 3, Tumor necrosis factor receptor superfamily member 3, Tumor necrosis factor receptor type III

ID gène: 4055

UniProt: P36941

Pathways: Signalisation NF-kappaB