CLN6 anticorps
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- Antigène Voir toutes CLN6 Anticorps
- CLN6 (Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CLN6 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- CLN6 antibody detects endogenous levels of CLN6 protein.(region surrounding asn258)
- Purification
- Affinity chromatography
- Top Product
- Discover our top product CLN6 Anticorps primaire
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- Indications d'application
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ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- CLN6 (Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6))
- Autre désignation
- CLN6 (CLN6 Produits)
- Synonymes
- anticorps 1810065L06Rik, anticorps AW743417, anticorps D9Bwg1455e, anticorps nclf, anticorps CLN4A, anticorps HsT18960, anticorps cln6, anticorps zgc:103565, anticorps ceroid-lipofuscinosis, neuronal 6, anticorps CLN6, transmembrane ER protein, anticorps CLN6, transmembrane ER protein S homeolog, anticorps ceroid-lipofuscinosis, neuronal 6, late infantile, variant, anticorps CLN6, transmembrane ER protein a, anticorps Cln6, anticorps CLN6, anticorps cln6.S, anticorps cln6a
- Sujet
- CLN6, a 311-amino acid protein, has 7 predicted transmembrane domains and is conserved across vertebrates. The CLN6 protein localizes to the endoplasmic reticulum but contributes to lysosomal function. Mutations in the CLN6 gene cause variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL), a lysosomal storage disorder marked by progressive mental deterioration and blindness, part of a group of severe inherited neurodegenerative disorders affecting children wherein lysosomes accumulate storage material, causing the death of neurons. CLN6 is one of eight proteins, including CLN1-8, that are associated with NCL.Synonyms: Ceroid-lipofuscinosis neuronal protein 6
- Poids moléculaire
- approx. 40 kDa
- ID gène
- 54982
- NCBI Accession
- NP_060352
- UniProt
- Q9NWW5
- Pathways
- Glycosaminoglycan Metabolic Process
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