TRHR anticorps

N° du produit ABIN317876

Détail du produit anti-TRHR anticorps

Antigène: TRHR (Thyrotropin-Releasing Hormone Receptor (TRHR))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRHR est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Affinity chromatography

Information d'application

Indications d'application: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TRHR

Antigène: TRHR (Thyrotropin-Releasing Hormone Receptor (TRHR))

Autre désignation: TRHR (TRHR Produits)

Synonymes: anticorps TRH-R1, anticorps TRH-R, anticorps GPCR, anticorps trhr-A, anticorps xtrhr, anticorps TRH-RECEPTOR, anticorps thyrotropin-releasing hormone receptor, anticorps thyrotropin releasing hormone receptor, anticorps thyrotropin releasing hormone receptor S homeolog, anticorps Tsp_09695, anticorps Trhr, anticorps TRHR, anticorps trhr.S

Sujet: Thyrotrophin-releasing hormone (TRH) is a hypothalamic tripeptide that stimulates, via its receptor in the anterior pituitary gland, the release of thyrotrophin (TSH) and prolactin. The TRH receptors, TRH-R1 and TRH-R2, are G protein-coupled proteins containing seven transmembrane domains and other conserved regions. In rat, two isoforms exist, TRH-R (412) and TRH-R (387), that differ at their carboxy termini. TRH receptors are distributed throughout the central and peripheral nervous systems and are present in a variety of tissues. TRH-R2 displays 50 % homology to TRH-R1 and is more restricted to the central nervous system than TRH-R1. Mutation in the TRH receptor gene is associated with isolated central hypothyroidism, a rare disorder characterized by insufficient TSH secretion resulting in low levels of thyroid hormones.Synonyms: TRH-R, Thyroliberin receptor 1, Thyrotropin-releasing hormone receptor

Poids moléculaire: approx. 50 kDa