MNDA anticorps

N° du produit ABIN317919

Détail du produit anti-MNDA anticorps

Antigène: MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MNDA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: MNDA antibody detects endogenous levels of MNDA protein.(region surrounding Val406)

Purification: Affinity chromatography

Information d'application

Indications d'application: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MNDA

Antigène: MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))

Autre désignation: MNDA (MNDA Produits)

Synonymes: anticorps PYHIN3, anticorps A730048F03, anticorps Ifi205b, anticorps myeloid cell nuclear differentiation antigen, anticorps interferon activated gene 211, anticorps MNDA, anticorps Ifi211

Sujet: Interferon-inducible proteins include IFI-202, IFI-203, IFI-204 and D3, which are encoded by six or more structurally related and IFN-inducible mouse genes mapping at the q21-q23 region of chromosome 1. The proteins encoded by these genes have homologous 200 amino acid segments. IFI-202 is a 52 kDa, primarily nuclear phosphoprotein which inhibits cell growth, in part by modulating transcriptional activity of NFκB, E2F, AP-1 and p53. Two related human proteins, MNDA (myeloid cell nuclear differentiation antigen) and IFI-16, have also been described. Expression of MNDA has been observed specifically in cells of the granulocyte-macrophage lineage. IFI-16 is constitutively expressed in various T and B cell lines and can be induced by IFN-γ in HL60 cells. At least four of the Gene 200 cluster of IFN-inducible proteins, IFI-202, IFI-204, MNDA and IFI-16, are localized in the nucleus.Synonyms: Myeloid cell nuclear differentiation antigen

Poids moléculaire: approx. 46 kDa

ID gène: 4332

NCBI Accession: NP_002423

UniProt: P41218