PPP1R3C anticorps

N° du produit ABIN317934

Détail du produit anti-PPP1R3C anticorps

Antigène: PPP1R3C (Protein Phosphatase 1, Regulatory Subunit 3C (PPP1R3C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP1R3C est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of PTG protein.(region surrounding Lys75)

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PPP1R3C

Antigène: PPP1R3C (Protein Phosphatase 1, Regulatory Subunit 3C (PPP1R3C))

Autre désignation: PPP1R3C / PTG (PPP1R3C Produits)

Synonymes: anticorps PPP1R5, anticorps PTG, anticorps Ppp1r5, anticorps R5, anticorps ppp1r3c, anticorps zgc:73259, anticorps cb444, anticorps fc19f02, anticorps sb:cb444, anticorps wu:fb50a11, anticorps wu:fc17c07, anticorps wu:fc19f02, anticorps zgc:92069, anticorps protein phosphatase 1 regulatory subunit 3C, anticorps protein phosphatase 1, regulatory (inhibitor) subunit 3C, anticorps protein phosphatase 1, regulatory subunit 3C, anticorps protein phosphatase 1, regulatory subunit 3Cb, anticorps protein phosphatase 1, regulatory subunit 3Ca, anticorps PPP1R3C, anticorps Ppp1r3c, anticorps ppp1r3cb, anticorps ppp1r3c, anticorps ppp1r3ca

Sujet: Protein phosphatase 1 (PP1) is a serine-threonine protein phosphatase that plays a central role in mediating the effects of insulin on glucose and lipid metabolism. PTG (protein targeting to glycogen) was cloned from 3T3-L1 adipocytes as a protein that binds to the PP1 catalytic subunit. The human homolog of PTG, designated PPP1R5, has been shown to bind to PP1 and to modulate its specificity. PTEN/PPP1R5 shows 42 % identity to the glycogen binding subunit, G(L), of rat liver PP1. PTG is expressed predominantly in insulin-sensitive tissues, and it localizes PP1 to glycogen. PTG also has been shown to interact with several enzymes involved in the hormonal regulation of glycogen metabolism, including phosphorylase kinase, phosphorylase A and glycogen synthase. These data indicate a role for PTG in glycogen metabolism, possibly that of a molecular scaffold.Synonyms: PPP1R5, Protein phosphatase 1 regulatory subunit 3C, Protein phosphatase 1 regulatory subunit 5, Protein targeting to glycogen

Poids moléculaire: approx. 36 kDa

ID gène: 5507

NCBI Accession: NP_005389

UniProt: Q9UQK1

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process