SEMA4D/CD100 anticorps (APC)

N° du produit ABIN319838

Détail du produit anti-SEMA4D/CD100 anticorps (APC)

Antigène: SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SEMA4D/CD100 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Immunogène: Human PHA activated lymphocytes. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.

Clone: A8

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: Use 10 μL of Neat-1/10 diluted antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 1 mL distilled water

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 5 % sucrose, 0.09 % Sodium Azide as preservative, 5 % Sucrose and 1 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: This product is photosensitive and should be protected from light

Stock: 4 °C

Stockage commentaire: Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE!

Détails sur SEMA4D/CD100

Antigène: SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))

Autre désignation: CD100 / SEMA4D (SEMA4D Produits)

Synonymes: anticorps C9orf164, anticorps CD100, anticorps M-sema-G, anticorps SEMAJ, anticorps coll-4, anticorps Semacl2, anticorps Semaj, anticorps Semcl2, anticorps COLL-4, anticorps semaphorin 4D, anticorps sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D, anticorps Sema4d, anticorps SEMA4D

Sujet: Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100 (also known as semaphorin 4d), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.Synonyms: A8, BB18, GR3, SEMAJ, Semaphorin-4D

ID gène: 9606

UniProt: Q92854

Pathways: Regulation of Cell Size