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CHEK1 anticorps

CHEK1 Reactivité: Humain, Souris WB, ELISA Hôte: Souris Monoclonal 2G1D5 unconjugated
N° du produit ABIN3209997
  • Antigène Voir toutes CHEK1 Anticorps
    CHEK1 (Checkpoint Kinase 1 (CHEK1))
    Reactivité
    • 215
    • 119
    • 68
    • 16
    • 9
    • 9
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 224
    • 14
    • 7
    • 5
    Souris
    Clonalité
    • 210
    • 41
    Monoclonal
    Conjugué
    • 135
    • 13
    • 11
    • 9
    • 9
    • 9
    • 9
    • 8
    • 8
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    Cet anticorp CHEK1 est non-conjugé
    Application
    • 173
    • 87
    • 54
    • 41
    • 40
    • 36
    • 35
    • 17
    • 16
    • 13
    • 10
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
     Réactivité croisée
    Souris
    Purification
    Purified antibody.
    Immunogène
    CHK1 antibody was raised in Mouse using a purified recombinant fragment of CHK1 expressed in E. coli as the immunogen.
    Clone
    2G1D5
    Isotype
    IgG1
    Top Product
    Discover our top product CHEK1 Anticorps primaire
  • Indications d'application
    ELISA: 1:10,000, WB: 1:500-1:2,000
    Optimal conditions should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    Lot specific
    Buffer
    Purified antibody supplied in PBS containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 4 °C for short term storage. Store at -20 °C for long term storage.
  • Antigène
    CHEK1 (Checkpoint Kinase 1 (CHEK1))
    Autre désignation
    CHK1 (CHEK1 Produits)
    Synonymes
    anticorps An08g10320, anticorps AO090003000441, anticorps CHK1, anticorps chk1, anticorps C85740, anticorps Chk1, anticorps rad27, anticorps id:ibd2720, anticorps zgc:56093, anticorps CHEK1, anticorps checkpoint kinase 1, anticorps serine/threonine-protein kinase chk1, anticorps serine/threonine-protein kinase Chk1, anticorps CAMK/CAMKL/CHK1 protein kinase Chk1, anticorps checkpoint kinase 1 S homeolog, anticorps CHEK1, anticorps ANI_1_2436074, anticorps AOR_1_768154, anticorps PTRG_04183, anticorps SJAG_01680, anticorps PAAG_04978, anticorps MCYG_03290, anticorps VDBG_03742, anticorps chek1.S, anticorps Chek1, anticorps chek1
    Sujet
    CHK1 is a kinase that phosphorylates Cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Cdc25, when phosphorylated on serine 216 by chk1 becomes bound by an adaptor protein in the cytoplasm. Therefore it is inhibited from removing the inhibiting phosphate from MPF (mitotic/maturation promoting factor) added by Wee1. Consequently, a cell is prevented from entering mitosis. Synonyms: Monoclonal CHK1 antibody, Anti-CHK1 antibody, CHK-1 antibody, CHK 1 antibody, CHEK1 antibody.
    Pathways
    Signalisation p53, Apoptose, Cycle Cellulaire, Réparation de l'ADN
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