RUNX3 anticorps (Internal Region)

N° du produit ABIN350815

Détail du produit anti-RUNX3 anticorps

Antigène: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Épitope: Internal Region

Reactivité: Souris, Rat

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp RUNX3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: Specific for Runx3.

Immunogène: A synthetic peptide from the internal region of rat Runt-related transcription factor 3 (Runx3) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in mouse.

Isotype: IgG

Information d'application

Indications d'application: A concentration of 10-50 µg/ml is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur RUNX3

Antigène: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Autre désignation: Runx3 (RUNX3 Produits)

Synonymes: anticorps runxb, anticorps RUNX3, anticorps CBFA3, anticorps frrunx3, anticorps runx3, anticorps aml2, anticorps cbfa3, anticorps pebp2ac, anticorps AML2, anticorps Cbfa3, anticorps Pebp2a3, anticorps PEBP2aC, anticorps runt-related transcription factor 3, anticorps runt related transcription factor 3, anticorps runt related transcription factor 3 L homeolog, anticorps runx3, anticorps RUNX3, anticorps runx3.L, anticorps Runx3

Sujet: Function: Binds to the core site of murine Leukemia virus, the core sequences in the enhancer of the polyomavirus, and also to the enhancers of the T-cell receptor genes. May be involved in the control of cellular proliferation and/or differentiation.
Subunit: Heterodimer of an alpha and a beta subunit. The alpha subunit binds DNA as a monomer and through the Runt domain. DNA-binding is increased by heterodimerization. Interacts with TLE1 and SUV39H1.
Subcellular location: Nucleus. Also known as: Runx3, Core-binding factor, alpha 3 subunit, CBF-alpha 3, Acute myeloid leukemia 2 protein, Oncogene AML-2, Polyomavirus enhancer-binding protein 2 alpha C subunit, PEBP2-alpha C, PEA2-alpha C, SL3-3 enhancer factor 1 alpha C subunit, SL3/AKV core-binding factor alpha C subunit.