TRPV1 anticorps (1st Cytoplasmic Loop)

N° du produit ABIN351259

Détail du produit anti-TRPV1 anticorps

Antigène: TRPV1 (Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1))

Épitope: 1st Cytoplasmic Loop

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRPV1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: Specific for TRPV1.

Immunogène: A synthetic peptide from the 1t cytoplasmic loop of mouse TRPV1 (VR1, capsaicin receptor, vanilloid receptor 1) conjugated to an immunogenic carrier protein was used as the immunogen.

Isotype: IgG

Information d'application

Indications d'application: A concentration of 10-50 µg/ml recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur TRPV1

Antigène: TRPV1 (Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1))

Autre désignation: TRPV1 (TRPV1 Produits)

Synonymes: anticorps si:dkey-9e15.2, anticorps VR.5'sv, anticorps Vr1, anticorps Vr1l1, anticorps VR1, anticorps OTRPC1, anticorps TRPV1alpha, anticorps TRPV1beta, anticorps VR-1, anticorps transient receptor potential cation channel, subfamily V, member 1, anticorps transient receptor potential cation channel subfamily V member 1, anticorps trpv1, anticorps Trpv1, anticorps TRPV1

Sujet: Function: Receptor-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. May be involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits a time- and Ca(2+)-dependent outward rectification, followed by a long-lasting refractory state. Mild extracellular acidic pH (6.5) potentiates channel activation by noxious heat and vanilloids, whereas acidic conditions (pH Also known as: Transient receptor potential cation channel subfamily V member 1, TrpV1, osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1, Vanilloid receptor type 1-like, Capsaicin receptor, transient receptor potential cation channel, subfamily V, member 1, Vr1, Vr1l1, VR.5'sv.

Pathways: Dicarboxylic Acid Transport