DAAM1 anticorps (C-Term, N-Term)

N° du produit ABIN357856

Détail du produit anti-DAAM1 anticorps

Antigène: DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))

Épitope: C-Term, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DAAM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects DAAM1 (C-term).

Purification: Protein A Chromatography followed by peptide affinity purification.

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human DAAM1.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur DAAM1

Antigène: DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))

Autre désignation: DAAM1 (DAAM1 Produits)

Synonymes: anticorps 1700066F09Rik, anticorps 2310028E21Rik, anticorps AI503486, anticorps E130308H01, anticorps mKIAA0666, anticorps daam-1, anticorps xdaam1, anticorps daam1, anticorps DAAM1, anticorps DKFZp468D0524, anticorps daam1l, anticorps fc83b10, anticorps si:ch211-87i20.1, anticorps wu:fc83b10, anticorps dishevelled associated activator of morphogenesis 1, anticorps dishevelled associated activator of morphogenesis 1 S homeolog, anticorps dishevelled associated activator of morphogenesis 1a, anticorps dishevelled associated activator of morphogenesis 1b, anticorps DAAM1, anticorps Daam1, anticorps daam1.S, anticorps daam1a, anticorps daam1, anticorps daam1b

Sujet: Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. DAAM1 contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by DAAM1, which is thought to function as a scaffolding protein.Synonyms: DAAM-1, Disheveled-associated activator of morphogenesis 1, FLJ41657, KIAA0666

Poids moléculaire: 123473 Da

ID gène: 23002, 9606

UniProt: Q9Y4D1

Pathways: Signalisation WNT