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ADAMTS4 anticorps (C-Term)

ADAMTS4 Reactivité: Humain, Souris WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN359602
  • Antigène Voir toutes ADAMTS4 Anticorps
    ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
    Épitope
    • 15
    • 11
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 80
    • 47
    • 20
    • 10
    • 9
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 72
    • 10
    • 4
    Lapin
    Clonalité
    • 77
    • 9
    Polyclonal
    Conjugué
    • 40
    • 10
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ADAMTS4 est non-conjugé
    Application
    • 63
    • 29
    • 15
    • 13
    • 13
    • 13
    • 11
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to ADAMTS4.
    Purification
    Protein A column, followed by peptide affinity purification
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ADAMTS4.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ADAMTS4 Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
    Autre désignation
    ADAMTS4 (ADAMTS4 Produits)
    Synonymes
    anticorps 3830423K05, anticorps ADAM-TS4, anticorps ADAMTS-2, anticorps ADMP-1, anticorps mKIAA0688, anticorps ADAMTS-4, anticorps ADAMTS4, anticorps a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4, anticorps ADAM metallopeptidase with thrombospondin type 1 motif 4, anticorps ADAM metallopeptidase with thrombospondin type 1 motif, 4, anticorps Adamts4, anticorps ADAMTS4
    Sujet
    ADAMTS4 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.Synonyms: A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAM-TS4, ADAMTS-4, ADMP-1, ADMP1, Aggrecanase-1, KIAA0688
    ID gène
    9507, 9606
    UniProt
    O75173
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