MAPK11 anticorps (Middle Region)

N° du produit ABIN359643

Cet anticorps anti-MAPK11 Polyclonal Lapin (ABIN359643) détecte spécifiquement MAPK11 dans EIA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MAPK11 anticorps (Middle Region) (ABIN359643)

Antigène: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK11 est non-conjugé

Application: Enzyme Immunoassay (EIA)

Détail du produit anti-MAPK11 anticorps

Épitope: Middle Region

Specificité: This antiobody reacts to p38 beta.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human P38beta.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur MAPK11

Antigène: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Autre désignation: MAP Kinase p38 beta / MAPK11

Sujet: P38 beta is a member of the MAP kinase subfamily of Ser/Thr protein kinases. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by changes in osmolarity of the extracellular environment, proinflammatory cytokines and cellular stress. This protein preferentially phosphorylates transcription factor ATF2. It is activated by phosphorylation on threonine and tyrosine by MKK6, and inhibited by pyridinyl-imidazole related compounds. Highest levels of expression are found in the brain and heart, with additional expression in the placenta, lung, liver, skeletal muscle, kidney and pancreas.Synonyms: Mitogen-activated protein kinase 11, PRKM11, SAPK2, Stress-activated protein kinase 2, p38-2

ID gène: 5600, 9606

UniProt: Q15759

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Response to Water Deprivation, Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Hepatitis C, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins