TRPM2 anticorps

N° du produit ABIN361540

Détail du produit anti-TRPM2 anticorps

Antigène: TRPM2 (Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRPM2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Purification: Antigen Affinity

Immunogène: Partial peptide of Mouse Trpm2 (C-terminal region)

Information d'application

Indications d'application: ELISA: 1ug/ml. WB: 1-5ug/ml. IHC: 5-10ug/ml. ICC: 1-5ug/ml.

Restrictions: For Research Use only

Stockage

Concentration: 0.25 mg/ml

Buffer: PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]

Agent conservateur: ProClin

Stock: -20 °C

Détails sur TRPM2

Antigène: TRPM2 (Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))

Autre désignation: Trpm2 (TRPM2 Produits)

Synonymes: anticorps EREG1, anticorps KNP3, anticorps LTRPC2, anticorps NUDT9H, anticorps NUDT9L1, anticorps TRPC7, anticorps Trpm2-predicted, anticorps TRPM2, anticorps si:ch73-263b18.1, anticorps 9830168K16Rik, anticorps C79133, anticorps Trp7, anticorps Trrp7, anticorps transient receptor potential cation channel subfamily M member 2, anticorps transient receptor potential cation channel, subfamily M, member 2, anticorps transient receptor potential cation channel subfamily C member 7, anticorps TRPM2, anticorps Trpm2, anticorps trpm2, anticorps TRPC7

Sujet: Function: Nonselective, voltage-independentcation channel mediating sodium and calcium ion influx in response to oxidative stress.Extracellularcalcium passes through the channel and acts from the intracellularside as a positive regulator in channel activation.Activatedby ADP-ribose, nicotinamide adenine dinucleotide (NAD+), reactive nitrogen species and arachidonic acid. Inactivated by intracellularATP. Confers susceptibility to cell death following oxidative stress. Has ADP-ribose pyrophosphatase activity Tissue specificity: Widely expressed, with highest levels in lung, spleen, eye and brain Sequence similarities: Belongs to the transient receptor family. LTrpC subfamily. Contains 1 nudix hydrolase domain.

ID gène: 28240