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TRPM2 Produits

(Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))

Catégories

The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008].

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Catégories TRPM2 en vedette

TRPM2 Anticorps

High quality antibodies with extensive validation data.

TRPM2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TRPM2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (6)
N° du produit ABIN7172859
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
N° du produit ABIN7172857
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (3)
N° du produit ABIN6149582
Quantité 100 μL
Fiche technique Fiche technique

TRPM2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3127490
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3074941
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3096095
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits TRPM2

Gattkowski, Johnsen, Bauche, Möckl, Kulow, Garcia Alai, Rutherford, Fliegert, Tidow: "Novel CaM-binding motif in its NudT9H domain contributes to temperature sensitivity of TRPM2." dans: Biochimica et biophysica acta. Molecular cell research, (2018) (PubMed).

Yee, Freestone, Bai, Lipski: "Paradoxical lower sensitivity of Locus Coeruleus than Substantia Nigra pars compacta neurons to acute actions of rotenone." dans: Experimental neurology, Vol. 287, Issue Pt 1, pp. 34-43, (2016) (PubMed).

Chung, Asgar, Lee, Shim, Dumler, Ro: "The role of TRPM2 in hydrogen peroxide-induced expression of inflammatory cytokine and chemokine in rat trigeminal ganglia." dans: Neuroscience, Vol. 297, pp. 160-9, (2015) (PubMed).

Rah, Kwak, Chung, Kim: "ADP-ribose/TRPM2-mediated Ca2+ signaling is essential for cytolytic degranulation and antitumor activity of natural killer cells." dans: Scientific reports, Vol. 5, pp. 9482, (2015) (PubMed).

Vaisitti, Audrito, Serra, Buonincontri, Sociali, Mannino, Pagnani, Zucchetto, Tissino, Vitale, Coscia, Usai, Pepper, Gattei, Bruzzone, Deaglio: "The enzymatic activities of CD38 enhance CLL growth and trafficking: implications for therapeutic targeting." dans: Leukemia, Vol. 29, Issue 2, pp. 356-68, (2015) (PubMed).

Roberge, Roussel, Andersson, Meli, Vidal, Blandel, Lanner, Le Guennec, Katz, Westerblad, Lacampagne, Fauconnier: "TNF-α-mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes." dans: Cardiovascular research, Vol. 103, Issue 1, pp. 90-9, (2014) (PubMed).

Lu, Xiang, Clemmer, Mittwede, Hester: "Oxidative stress increases pulmonary vascular permeability in diabetic rats through activation of transient receptor potential melastatin 2 channels." dans: Microcirculation (New York, N.Y. : 1994), Vol. 21, Issue 8, pp. 754-60, (2014) (PubMed).

Moreau, Kirchberger, Swarbrick, Bartlett, Fliegert, Yorgan, Bauche, Harneit, Guse, Potter: "Structure-activity relationship of adenosine 5'-diphosphoribose at the transient receptor potential melastatin 2 (TRPM2) channel: rational design of antagonists." dans: Journal of medicinal chemistry, Vol. 56, Issue 24, pp. 10079-102, (2013) (PubMed).

Melzer, Hicking, Göbel, Wiendl: "TRPM2 cation channels modulate T cell effector functions and contribute to autoimmune CNS inflammation." dans: PLoS ONE, Vol. 7, Issue 10, pp. e47617, (2012) (PubMed).

Chung, Freestone, Lipski: "Expression and functional properties of TRPM2 channels in dopaminergic neurons of the substantia nigra of the rat." dans: Journal of neurophysiology, Vol. 106, Issue 6, pp. 2865-75, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à TRPM2

transient receptor potential cation channel subfamily M member 2 (TRPM2), transient receptor potential cation channel, subfamily M, member 2 (Trpm2), transient receptor potential cation channel, subfamily M, member 2 (trpm2), transient receptor potential cation channel subfamily C member 7 (TRPC7), transient receptor potential cation channel subfamily M member 2 (trpm2), transient receptor potential cation channel subfamily M member 2 (Trpm2), 9830168K16Rik, C79133, EREG1, KNP3, LTRPC2, NUDT9H, NUDT9L1, si:ch73-263b18.1, Trp7, TRPC7, TRPM2, Trpm2-predicted, Trrp7

Protein level used designations for TRPM2

  • LTrpC-2
  • estrogen-responsive element-associated gene 1 protein
  • long transient receptor potential channel 2
  • transient receptor potential cation channel subfamily M member 2
  • transient receptor potential channel 7
  • transient receptor potential melastatin family 2
  • transient receptor potential cation channel, subfamily M, member 2
  • transient receptor potential cation channel, subfamily C, member 7
  • transient receptor potential cation channel, subfamily C, member 7-like
  • transient receptor potential cation channel subfamily M member 2-like
  • transient receptor protein 7
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