SHP1 anticorps (AA 534-538)
Aperçu rapide pour SHP1 anticorps (AA 534-538) (ABIN363036)
Antigène
Voir toutes SHP1 (PTPN6) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 534-538
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Specificité
- The antibody detects endogenous level of total SHP-1 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
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Immunogène
- Peptide sequence around AA 534-538 (S-E-Y-G-N) derived from Human SHP-1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Isotype
- IgG
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Indications d'application
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
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Autre désignation
- SHP-1
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Sujet
- Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.
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Poids moléculaire
- 68 kDa
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NCBI Accession
- NP_002822
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UniProt
- P29350
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Pathways
- Signalistation JAK/STAT, TCR Signaling, Signalisation TLR, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling
Antigène
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