MAP1LC3A anticorps (N-Term)

N° du produit ABIN363515

Détail du produit anti-MAP1LC3A anticorps

Antigène: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Épitope: AA 1-100, N-Term

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Bactéries

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP1LC3A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Specificité: Reacts withLC3 from human, mouse, rat, bacteria, golden syrian hamster, porcine and zebrafish

Purification: Antigen affinity purified

Immunogène: Synthetic peptide made to an N-terminal portion of the human LC3 protein sequence (between residues 1-100)

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB0.5-2 μg/mL ICC/IF1:200 IHC1:200-1:400 IP20 μg/500 μg of protein

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Tris-glycine, 150 mM NaCl, Sodium azide 0.05 %

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C/-80 °C

Stockage commentaire: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Détails sur MAP1LC3A

Antigène: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Autre désignation: Light Chain 3 (LC3) (MAP1LC3A Produits)

Synonymes: anticorps ATG8E, anticorps LC3, anticorps LC3A, anticorps MAP1ALC3, anticorps MAP1BLC3, anticorps 1010001H21Rik, anticorps 4922501H04Rik, anticorps LC3a, anticorps MGC69006, anticorps zgc:77094, anticorps MGC89867, anticorps MAP1LC3A, anticorps map1lc3a, anticorps microtubule associated protein 1 light chain 3 alpha, anticorps microtubule-associated protein 1 light chain 3 alpha, anticorps microtubule associated protein 1 light chain 3 alpha S homeolog, anticorps MAP1LC3A, anticorps Map1lc3a, anticorps map1lc3a.S, anticorps map1lc3a

Sujet: Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.

ID gène: 81631

Pathways: Autophagy