TYMS anticorps

N° du produit ABIN372202

Détail du produit anti-TYMS anticorps

Antigène: TYMS (Thymidylate Synthetase (TYMS))

Reactivité: Humain

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp TYMS est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Thymidylate Synthetase (TYMS).

Purification: IgG Fractionation.

Immunogène: Recombinant human Thymidylate Synthase (36 kD) produced in E. coli.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western Blot. Immunoprecipitation. Immunofluorescence. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Restore with distilled water.

Concentration: 10.0 mg/mL (after resuspension)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur TYMS

Antigène: TYMS (Thymidylate Synthetase (TYMS))

Autre désignation: Thymidylate Synthase (TS) (TYMS Produits)

Synonymes: anticorps FN1, anticorps ECK2823, anticorps JW2795, anticorps ts, anticorps Ts, anticorps HST422, anticorps TMS, anticorps TS, anticorps thymidylate synthetase, anticorps contains intron in T4 phage, anticorps ThyE, anticorps thymidylate synthase, anticorps thymidylate synthetase L homeolog, anticorps TYMS, anticorps thyA, anticorps td, anticorps thyE, anticorps DDA3937_RS04960, anticorps tyms.L, anticorps XBJ1_RS15770, anticorps EAMY_RS20680, anticorps Tyms

Classe de substances: Viral Protein

Sujet: Thymidylate synthase (TS) is an intracellular enzyme critical for de novo synthesis of DNA. In cancer, expression of TS is often elevated and becomes further elevated as a result of treatment with the most commonly used chemotherapeutic, 5-fluorouracil (5-FU). Resistance or lack of response to 5-FU is attributed to the elevation of TS activity. Overexpression of TS has been demonstrated in many types of tumors including breast, colon, gastric and melanoma and is usually predictive of shortened survival time.Synonyms: OK/SW-cl.29, TSase, TYMS

ID gène: 7298

NCBI Accession: NP_001062

UniProt: P04818

Pathways: Mitotic G1-G1/S Phases