BAK1 anticorps (N-Term)
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- Antigène Voir toutes BAK1 Anticorps
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Porc
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BAK1 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Séquence
- ASGQGPGPPR QE-C
- Specificité
- This antibody detects Bcl-2-like 7 at N-term.
- Purification
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
- Immunogène
- Peptide from N Terminus of the protein sequence according to NP_001179.1 Genename: BAK1
- Top Product
- Discover our top product BAK1 Anticorps primaire
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- Indications d'application
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Peptide ELISA: Limit dilution 1: 32000. Western Blot: 0.5-1 μg/mL. Approx 25 kDa band seen in A431 cell lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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MicroRNA-29c Correlates with Neuroprotection Induced by FNS by Targeting Both Birc2 and Bak1 in Rat Brain after Stroke." dans: CNS neuroscience & therapeutics, Vol. 21, Issue 6, pp. 496-503, (2016) (PubMed).
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MicroRNA-29c Correlates with Neuroprotection Induced by FNS by Targeting Both Birc2 and Bak1 in Rat Brain after Stroke." dans: CNS neuroscience & therapeutics, Vol. 21, Issue 6, pp. 496-503, (2016) (PubMed).
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- Antigène
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
- Autre désignation
- Bcl-2-Like 7 (BAK1 Produits)
- Synonymes
- anticorps BAK, anticorps BAK-LIKE, anticorps BCL2L7, anticorps CDN1, anticorps Bak, anticorps N-BAK1, anticorps N-Bak, anticorps Bak1, anticorps bak, anticorps bak1, anticorps BCL2 antagonist/killer 1, anticorps BCL2-antagonist/killer 1, anticorps BCL2 antagonist/killer 1 L homeolog, anticorps BAK1, anticorps Bak1, anticorps bak1.L
- Sujet
- Bak or Bcl2 homologous antagonist is a member of the Bcl2 family of proteins. The Bcl-2 related proteins interact with one another through the formation of homo and heterodimers. The susceptibility of cells to apoptotic stimuli is thought to be controlled by the relative ratios of the different Bcl2 family proteins. Bak has been demonstrated to accelerate the rate of apoptosis in growth factor deprived murine lymphoid, neuronal and fibroblastic cell lines. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. Bak also interacts with the tumor suppressor P53 after exposure to cell stress.Synonyms: Apoptosis regulator BAK, BAK, BAK1, BCL2L7, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 7, Bcl2-L-7, CDN1, cell death inhibitor 1
- ID gène
- 578
- NCBI Accession
- NP_001179
- UniProt
- Q16611
- Pathways
- Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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