CDT1 anticorps (C-Term)
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- Antigène Voir toutes CDT1 Anticorps
- CDT1 (Chromatin Licensing and DNA Replication Factor 1 (CDT1))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CDT1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- C-ARLAHQTRAE EGL
- Specificité
- This antibody detects CDT1 at C-term.
- Réactivité croisée (Details)
- Species reactivity (tested):Human
- Purification
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
- Immunogène
- Peptide from C Terminus of the protein sequence according to NP_112190.2. Genename: CDT1
- Top Product
- Discover our top product CDT1 Anticorps primaire
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- Indications d'application
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Peptide ELISA: Limit dilution 1: 64000. Western Blot: 1-3 μg/mL. Approx 65 kDa band observed in Human Brain lysates (predictedMW of 65 kDa according to NP_112190.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- Antigène
- CDT1 (Chromatin Licensing and DNA Replication Factor 1 (CDT1))
- Autre désignation
- CDT1 (CDT1 Produits)
- Synonymes
- anticorps CDT1, anticorps fc37h07, anticorps im:7158083, anticorps wu:fc37h07, anticorps wu:fi38h09, anticorps xcdt1, anticorps DUP, anticorps RIS2, anticorps 2610318F11Rik, anticorps AW545653, anticorps C76791, anticorps Ris2, anticorps dup, anticorps ris2, anticorps chromatin licensing and DNA replication factor 1, anticorps chromatin licensing and DNA replication factor 1 L homeolog, anticorps CDT1, anticorps cdt1, anticorps Cdt1, anticorps cdt1.L
- Sujet
- Cdt1 and its inhibitor Geminin are important regulators of replication licensing. A critical balance between both proteins functions to ensure that each origin only fires once during the cell cycle. Cdt1 cooperates with Cdc6 to promote the loading of the MCM complex onto chromatin to form the pre-replication complex. Overexpression of Cdt1 leads to aberrant replication and activation of DNA damage checkpoints. It is also associated with a predisposition for malignant transformation.Synonyms: DNA replication factor Cdt1, DUB, Double parked homolog, RIS2
- ID gène
- 81620
- NCBI Accession
- NP_112190
- UniProt
- Q9H211
- Pathways
- Signalisation MAPK, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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