FOXL2 anticorps (C-Term)

N° du produit ABIN374339

Détail du produit anti-FOXL2 anticorps

Antigène: FOXL2 (Forkhead Box L2 (FOXL2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXL2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Séquence: C-DSKTGALHSR LDL

Specificité: This antibody detects FOXL2 at C-term.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Cow, Rat.
Species reactivity (tested):Human.

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from C Terminus of the protein sequence according to NP_075555.1 Genename: FOXL2

Information d'application

Indications d'application: Peptide ELISA: Limit dilution 1: 16000. Western blot: 1-2 μg/mL. Approx 45-50 kDa band observed in Human Ovary extracts(predicted MW of 40 kDa according to NP_075555).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Détails sur FOXL2

Antigène: FOXL2 (Forkhead Box L2 (FOXL2))

Autre désignation: FOXL2 (FOXL2 Produits)

Synonymes: anticorps BPES, anticorps BPES1, anticorps PFRK, anticorps PINTO, anticorps POF3, anticorps AU045128, anticorps Pfrk, anticorps FOXL2, anticorps zgc:136549, anticorps foxl2, anticorps FoxL2, anticorps foxL2, anticorps forkhead box L2, anticorps forkhead box L2a, anticorps forkhead box L2 S homeolog, anticorps forkhead transcription factor L2, anticorps foxl2 protein, anticorps fork-head box L2 transcription factor, anticorps FOXL2, anticorps Foxl2, anticorps foxl2a, anticorps foxl2, anticorps foxl2.S, anticorps LOC751846, anticorps foxL2

Sujet: There are 2 forms of the blepharophimosis/ptosis/epicanthus inversus syndrome. In one form, called type I, eyelid abnormalities are associated with ovarian failure. In the second type, called type II, only the eyelid defects are found. Both types map to 3q23. Crisponi et al. (2001) refined the physical mapping of the BPES critical region and positionally cloned a novel, putative winged helix/forkhead transcription factor gene, FOXL2, in which they found mutations to produce truncated proteins in type I families and larger proteins in type II. Consistent with an involvement in those tissues, FOXL2 was selectively expressed in the mesenchyme of developing mouse eyelids and in adult ovarian follicles, in adult humans, it appeared predominantly in the ovary.Synonyms: Forkhead box protein L2

ID gène: 668

NCBI Accession: NP_075555

UniProt: P58012

Pathways: Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity