KDM2B anticorps (C-Term)

N° du produit ABIN374346

Détail du produit anti-KDM2B anticorps

Antigène: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Épitope: C-Term

Reactivité: Humain, Souris, Chien, Rat

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM2B est non-conjugé

Application: Western Blotting (WB)

Séquence: C-FGQVEEKLLQ KLS

Specificité: This antibody detects FBXL10 / PCCX2 at C-term. It is expected to recognize isoform a (NP_115979.3) only.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, DogSpecies reactivity (tested):Human

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from C Terminus of the protein sequence according to NP_115979.3 Genename: KDM2B

Information d'application

Indications d'application: Peptide ELISA: Limit dilution 1: 32000. Western blot: 1-3 μg/mL. Customer's experiments gave bands at approx 170+90 kDa inlysates of cell line HeLa (calculated MW of 150 kDa according to NP_115979.3).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Détails sur KDM2B

Antigène: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Autre désignation: KDM2B / FBXL10 (KDM2B Produits)

Synonymes: anticorps CXXC2, anticorps FBXL10, anticorps Fbl10, anticorps JHDM1B, anticorps PCCX2, anticorps fbxl10, anticorps wu:fd13a09, anticorps zgc:85787, anticorps KDM2B, anticorps Fbxl10, anticorps Cxxc2, anticorps E430001G17, anticorps Jhdm1b, anticorps mKIAA3014, anticorps jhdm1b, anticorps F6P23.18, anticorps F6P23_18, anticorps lysine demethylase 2B, anticorps lysine (K)-specific demethylase 2Ba, anticorps microRNA 7107, anticorps lysine (K)-specific demethylase 2B, anticorps lysine (K)-specific demethylase 2B L homeolog, anticorps F-box/RNI-like superfamily protein, anticorps KDM2B, anticorps kdm2ba, anticorps Kdm2b, anticorps MIR7107, anticorps kdm2b.L, anticorps AT2G17020

Sujet: KDM2B is a histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylted H3 'Lys-36'. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.Synonyms: CXXC-type zinc finger protein 2, CXXC2, F-box and leucine-rich repeat protein 10, F-box protein FBL10, F-box/LRR-repeat protein 10, FBL10, JEMMA, JHDM1B, JmjC domain-containing histone demethylation protein 1B, Jumonji domain-containing EMSY-interactor methyltransferase motif protein, Lysine-specific demethylase 2B, PCCX2, Protein-containing CXXC domain 2, [Histone-H3]-lysine-36 demethylase 1B

ID gène: 84678

NCBI Accession: NP_115979

UniProt: Q8NHM5

Pathways: Tube Formation, L'effet Warburg