MSX1 anticorps (N-Term)

N° du produit ABIN374442

Détail du produit anti-MSX1 anticorps

Antigène: MSX1 (Msh Homeobox 1 (MSX1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp MSX1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: TSLPLGVKVE DS-C

Specificité: Recognizes MSX1 (N-term).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, and Cow.
Species reactivity (tested):Human.

Purification: Ammonium sulphate precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide from the N Terminus of the protein sequence according to NP_002439.1.

Information d'application

Indications d'application: Peptide ELISA: Antibody Detection Limit Dilution: 1/16000. Western blot: Preliminary experiments gave an approx.55-60 kDa band in Human Muscleand Heart lysates at 1 μg/mL. Further, this band was successfully blocked byincubation with the immunising peptide. Please note that currently we cannot find anexplanation in the literature for the band we observe given the predicted size of approx.31.0 kDa according to Human NP_002439.2. Immunohistochemistry: 2-4 μg/mL. In paraffin embedded Human Prostate shows staining of nucleoli in a few epithelial cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.

Détails sur MSX1

Antigène: MSX1 (Msh Homeobox 1 (MSX1))

Autre désignation: MSX1 (MSX1 Produits)

Synonymes: anticorps ECTD3, anticorps HOX7, anticorps HYD1, anticorps STHAG1, anticorps AA675338, anticorps AI324650, anticorps Hox-7, anticorps Hox7, anticorps Hox7.1, anticorps msh, anticorps CHOX-7, anticorps GHOX-7, anticorps HOX-7, anticorps msh homeobox 1, anticorps MSX1, anticorps Msx1

Sujet: MSX1 is a transcriptional repressor that belongs to the Msh homeobox family. It plays a role in cranofacial development, specifically in odontogenesis. A Sonic hedgehog-controlled cascade that includes MSX1 acts in parallel with the Wnt1 network to establish the midbrain dopaminergic progenitor domain, which gives rise to a neuronal population that is critical for normal function of the human brain and is involved in a number of neurological and psychiatric diseases, such as Parkinson's disease.Synonyms: HOX7, Homeobox protein Hox-7, Homeobox protein MSX-1, Hox-7, MSX-1, Msh homeobox 1-like protein

ID gène: 4487, 9606

UniProt: P28360

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Response to DNA Damage Stimulus