COMT anticorps (N-Term)

N° du produit ABIN374503

Détail du produit anti-COMT anticorps

Antigène: COMT (Catechol-O-Methyltransferase (COMT))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp COMT est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody is expected to recognise both reported isoforms. Variants (NP_000745.1, NP_001128633.1 and NP_001128634.1) encode the same isoform.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat and Canine (Dog).
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence GDTKEQRILNHVLQC, from the N-Terminus of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: Detection Limit Dilution: 1/4000. Western Blot: 0.3-1.0 μg/mL. Approx 26 kDa plus 26 kDa bands observed in Human Testislysates (calculated MW of 30.6 kDa according to NP_000745.1 and of 24.6 kDa according toNP_009294.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur COMT

Antigène: COMT (Catechol-O-Methyltransferase (COMT))

Autre désignation: COMT (COMT Produits)

Synonymes: anticorps Comt1, anticorps D16Wsu103e, anticorps D330014B15Rik, anticorps COMT, anticorps mb-comt, anticorps s-comt, anticorps comt, anticorps MGC154444, anticorps zgc:114157, anticorps si:dkey-13a21.15, anticorps zK13A21.15, anticorps zgc:162236, anticorps catechol-O-methyltransferase, anticorps microRNA 4761, anticorps catechol-O-methyltransferase S homeolog, anticorps methyltransferase, anticorps catechol-o-methyltransferase, anticorps catechol-O-methyltransferase a, anticorps catechol-O-methyltransferase b, anticorps catechol O-methyltransferase, anticorps COMT, anticorps Comt, anticorps MIR4761, anticorps comt, anticorps comt.2, anticorps comt.S, anticorps Rv1703c, anticorps Mb1729c, anticorps comta, anticorps comtb, anticorps LOC100354142

Sujet: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease.Synonyms: Catechol O-methyltransferase

ID gène: 1312, 9606

UniProt: P21964

Pathways: Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome