Neuroserpin anticorps (C-Term)
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- Antigène Voir toutes Neuroserpin (SERPINI1) Anticorps
- Neuroserpin (SERPINI1) (serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Chimpanzé
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Neuroserpin est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody reacts to Neuroserpin.
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Rat, Bovine.
Species reactivity (tested):Human. - Purification
- Affinity chromatography
- Immunogène
- Peptide with sequence C-TMNTSGHDFEEL, from the C Terminus of the protein sequence
- Top Product
- Discover our top product SERPINI1 Anticorps primaire
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- Indications d'application
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Peptide ELISA: 1/32000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0,5 mg/mL
- Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- Neuroserpin (SERPINI1) (serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1))
- Autre désignation
- Neuroserpin / SERPINI1 (SERPINI1 Produits)
- Synonymes
- anticorps PI12, anticorps neuroserpin, anticorps AI837402, anticorps Ns, anticorps PI-12, anticorps Spi17, anticorps CG9453, anticorps Dmel\\CG9453, anticorps Serp2, anticorps Sp4, anticorps Spn4, anticorps Spn4A, anticorps dSerp2, anticorps sp4, anticorps spn4, anticorps raPIT5a, anticorps SERPINI1, anticorps pi12, anticorps serpini1l, anticorps si:ch211-167c22.4, anticorps serpin family I member 1, anticorps serine (or cysteine) peptidase inhibitor, clade I, member 1, anticorps Serpin 42Da, anticorps serpin peptidase inhibitor, clade I (neuroserpin), member 1, anticorps serpin family I member 1 L homeolog, anticorps SERPINI1, anticorps Serpini1, anticorps Spn42Da, anticorps serpini1, anticorps serpini1.L
- Sujet
- Neuroserpin is a member of the serpin superfamily and is predominantly expressed by neurons of the developing and adult brain. This serpin is secreted from axonal growth cones of the CNS and PNS where it inhibits the enzyme tissue plasminogen activator. The expression pattern of neuroserpin and its in vivo inhibitory activity implicate this serpin in regulating axonal growth, reducing seizure activity, controlling damage in cerebral infarction and regulating emotional behaviour and memory. Four different mutations have been described in the human neuroserpin gene that promote neuroserpin abnormal polymerization, giving rise to intraneuronal inclusion bodies and a new form of dementia called Familial Encephalopathy with Neuroserpin Inclusion Bodies.Synonyms: PI-12, PI12, Peptidase inhibitor 12, Serpin I1
- ID gène
- 5274, 9606
- UniProt
- Q99574
- Pathways
- Regulation of Hormone Metabolic Process
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