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Arrestin 3 anticorps (Internal Region)

ARRB2 Reactivité: Humain, Souris, Rat WB, IP, IHC (p), EIA Hôte: Chèvre Polyclonal unconjugated
N° du produit ABIN374557
  • Antigène Voir toutes Arrestin 3 (ARRB2) Anticorps
    Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
    Épitope
    • 15
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 48
    • 27
    • 26
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 40
    • 5
    • 3
    Chèvre
    Clonalité
    • 43
    • 5
    Polyclonal
    Conjugué
    • 29
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Arrestin 3 est non-conjugé
    Application
    • 40
    • 18
    • 16
    • 13
    • 13
    • 12
    • 12
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Séquence
    C-HDHIPLPRPQ S
    Specificité
    This antibody is expected to recognizse both reported isoforms NP_004304.1 and NP_945355.1. No cross-reactivity is expected with Arrestin beta 1.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, Mouse, Rat.
    Purification
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    Immunogène
    Peptide with sequence from the internal region of the protein sequence according to NP_004304.1, NP_945355.1. Genename: ARRB2
    Top Product
    Discover our top product ARRB2 Anticorps primaire
  • Indications d'application
    Peptide ELISA: 1/32000. Western Blot: 0.3 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Cassidy, Slyne, OKelly, Traynor, Conlon, Johnston, Slattery, Ryan, McMorrow: "Urinary biomarkers of chronic allograft nephropathy." dans: Proteomics. Clinical applications, Vol. 9, Issue 5-6, pp. 574-85, (2015) (PubMed).

    Montserrat, Ramírez-Bajo, Xia, Sancho-Martinez, Moya-Rull, Miquel-Serra, Yang, Nivet, Cortina, González, Izpisua Belmonte, Campistol: "Generation of induced pluripotent stem cells from human renal proximal tubular cells with only two transcription factors, OCT4 and SOX2." dans: The Journal of biological chemistry, Vol. 287, Issue 29, pp. 24131-8, (2012) (PubMed).

    Zakrzewicz, Krasteva, Wilhelm, Dietrich, Wilker, Padberg, Wygrecka, Grau: "Reduced expression of arrestin beta 2 by graft monocytes during acute rejection of rat kidneys." dans: Immunobiology, Vol. 216, Issue 7, pp. 854-61, (2011) (PubMed).

  • Antigène
    Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
    Autre désignation
    Arrestin beta-2 / ARRB2 (ARRB2 Produits)
    Synonymes
    anticorps ARRB2, anticorps arb2, anticorps arr2, anticorps arrestin, anticorps barr2, anticorps betaarr2, anticorps ARB2, anticorps ARR2, anticorps BARR2, anticorps BARRES, anticorps AI326910, anticorps AW122872, anticorps arrb2, anticorps zgc:64007, anticorps arrestin beta 2, anticorps arrestin, beta 2, anticorps arrestin beta 2 L homeolog, anticorps arrestin, beta 2b, anticorps ARRB2, anticorps arrb2, anticorps Arrb2, anticorps arrb2.L, anticorps arrb2b
    Sujet
    Members of arrestin/beta arrestin protein family are thought to participate in agonist mediated desensitization of G protein coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors.Synonyms: ARB2, ARR2, Beta-arrestin-2
    Poids moléculaire
    46.1 kDa according to NP_004304.1 and 44.4 according to NP_945355.1.
    ID gène
    409, 9606
    UniProt
    P32121
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling
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