NR0B1 anticorps (Internal Region)
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- Antigène Voir toutes NR0B1 Anticorps
- NR0B1 (Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1))
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Épitope
- Internal Region
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Reactivité
- Humain
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NR0B1 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody reacts to DAX1 / NR0B1.
- Purification
- Affinity chromatography
- Immunogène
- Peptide with sequence CGEDHPQQGSTLY, from the internal region of the protein sequence
- Top Product
- Discover our top product NR0B1 Anticorps primaire
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- Indications d'application
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Peptide ELISA: 1/32000. Western Blot: 0.5 - 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0,5 mg/mL
- Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- NR0B1 (Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1))
- Autre désignation
- NR0B1 (NR0B1 Produits)
- Synonymes
- anticorps DAX, anticorps NR0B1, anticorps dax1, anticorps AHC, anticorps AHCH, anticorps AHX, anticorps DAX-1, anticorps DAX1, anticorps DSS, anticorps GTD, anticorps HHG, anticorps NROB1, anticorps SRXY2, anticorps Ahc, anticorps Ahch, anticorps Dax1, anticorps nuclear receptor subfamily 0 group B member 1, anticorps nuclear receptor subfamily 0, group B, member 1, anticorps nuclear receptor subfamily 0 group B member 1 L homeolog, anticorps NR0B1, anticorps nr0b1, anticorps nr0b1.L, anticorps Nr0b1
- Sujet
- NR0B1 is a receptor that may be a component of a cascade required for development of steroidogenic tissues. It acts as a dominant negative regulator of transcription mediated by the retinoic acid receptor. It interacts with COPS2. Defects in NR0B1 are the cause of X-linked adrenal hypoplasia congenital (AHC). AHC is a developmental disorder of the adrenal gland that results in profound hormonal deficiencies and is lethal if untreated. It is characterized by the absence of the permanent zone of the adrenal cortex and by a structural disorganization of the glands. Hypogonadotropic hypogonadism (HHG) is frequently associated with this disorder. HHG is a condition resulting from or characterized by abnormally decreased gonadal function, with retardation of growth and sexual development.Synonyms: AHC, DAX1, DSS-AHC critical region on the X chromosome protein 1, Nuclear receptor DAX-1, Nuclear receptor subfamily 0 group B member 1
- ID gène
- 190
- NCBI Accession
- NP_000466
- UniProt
- P51843
- Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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