CYLD anticorps (Internal Region)

N° du produit ABIN374832

Détail du produit anti-CYLD anticorps

Antigène: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Épitope: Internal Region

Reactivité: Souris, Rat

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp CYLD est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to Cyld.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-DSQQSKSKNPWYIDE, from the internal region of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/32000. Western Blot: 0.5 - 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CYLD

Antigène: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Autre désignation: CYLD (CYLD Produits)

Synonymes: anticorps BRSS, anticorps CDMT, anticorps CYLD1, anticorps CYLDI, anticorps EAC, anticorps MFT, anticorps MFT1, anticorps SBS, anticorps TEM, anticorps USPL2, anticorps 2010013M14Rik, anticorps 2900009M21Rik, anticorps C130039D01Rik, anticorps mKIAA0849, anticorps cyld, anticorps LRRGT00003, anticorps Rp1, anticorps Rp1h, anticorps CYLD lysine 63 deubiquitinase, anticorps cylindromatosis (turban tumor syndrome), a, anticorps CYLD, anticorps Cyld, anticorps cylda

Sujet: Defects in CYLD are the cause of familial cylindromatosis (CYLD) also known as turban tumor syndrome or dermal eccrine cylindromatosis. CYLD is an autosomal dominant and highly tumor type-specific disorder. The tumors (known as cylindromas because of their characteristic microscopic architecture) are believed to arise from or recapitulate the appearance of the eccrine or apocrine cells of the skin that secrete sweat and scent respectively. Cylindromas arise predominantly in hairy parts of the body with approximately 90 % on the head and neck. The development of a confluent mass which may ulcerate or become infected has led to the designation "turban tumor syndrome". The skin tumors show differentiation in the direction of hair structures, hence the synonym trichoepithelioma. CYLD has deubiquitinating activity.Synonyms: CYLD, CYLD1, Deubiquitinating enzyme CYLD, EC=3.1.2.15, KIAA0849, Ubiquitin carboxyl-terminal hydrolase CYLD, Ubiquitin thioesterase CYLD, Ubiquitin-specific-processing protease CYLD

ID gène: 1540

NCBI Accession: NP_001035814

UniProt: Q9NQC7

Pathways: Apoptose, Activation of Innate immune Response