GPX3 anticorps (Internal Region)

N° du produit ABIN374849

Détail du produit anti-GPX3 anticorps

Antigène: GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp GPX3 est non-conjugé

Application: Western Blotting (WB)

Séquence: C-NQFGKQEPGE NSE

Specificité: This antibody may cross-react with epididymis-specific GPX5 and olfactory epithelium-speciific GPX6.

Réactivité croisée (Details): Species reactivity (expected):Human, Rat, Canine.
Species reactivity (tested):Mouse.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_002075.2.

Information d'application

Indications d'application: Peptide ELISA: Limit dilution: 1/1000. Western Blot: 1-3 μg/mL. Approx 26 kDa band observed in Mouse Kidney and Liver lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GPX3

Antigène: GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))

Autre désignation: Glutathione Peroxidase 3 / GPX3 (GPX3 Produits)

Synonymes: anticorps GPX3, anticorps DKFZp469D1932, anticorps AA960521, anticorps EGPx, anticorps GPx, anticorps GSHPx-3, anticorps GSHPx-P, anticorps GPx-3, anticorps GPx-P, anticorps Gpxp, anticorps glutathione peroxidase 3, anticorps gpx3, anticorps GPX3, anticorps Gpx3

Sujet: Glutathione peroxidases(Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organichydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPxfamily to be discovered. GPx2, also known as gastrointestinal GPx(GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract.Extracellular plasma GPx(pGPxor GPx3) is mainly expressed by the kidney from where it is released into the blood. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxylipids in low density lipoprotein orthymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx(eGPxor GPx5)isoforms, possess selenocysteine at the active site.Synonyms: Extracellular glutathione peroxidase, GPX-3, GPXP, GPx-3, GPx-P, GSHPXP, GSHPx-3, GSHPx-P, Glutathione peroxidase-3, Plasma glutathione peroxidase

ID gène: 2878

NCBI Accession: NP_002075

UniProt: P22352

Pathways: Thyroid Hormone Synthesis